The first half saw end-to-end action with both teams getting their fair share of chances to break the deadlock. In the eighth minute, Monaco star Pavlidis initiated a brilliant counter-attack after intercepting the ball in the centre of the pitch. He linked up with Fredrik Aursnes, but the midfielder's return pass was easily intercepted by Monaco defender Thilo Kehrer. A minute later, Aleksandr Golovin launched a powerful strike on goal which forced Benfica custodian Anatoliy Trubin to go full stretch to parry the ball away.
The visitors finally broke the deadlock three minutes after the break as Pavlidis received a through ball from Tomas Araujo down the right flank. The Greek forward went past his marker inside the Monaco boss before chipping the ball over Radosław Majecki to his side the lead.
Things went from bad to worse for the hosts in the 52nd minute when Moatasem Al-Musrati picked up his second yellow card of the match for dissent after he got into a tangle with Breel Embolo.
Roger Schmidt brought in veteran Argentine winger Angel Di Maria in the 67th minute but the ex-Real Madrid and Manchester United star lasted only 20 minutes on the pitch as he limped off with an injury.