Spurs said in a statement: “The club is aware of abhorrent homophobic chanting from sections of our away support at Old Trafford today.
“This is simply unacceptable, hugely offensive and no way to show support for the team.
“The club will be working closely with the police and stewards to identify anyone instigating or joining in with the chanting — we shall take the strongest possible action in accordance with our sanctions and banning policy.”