Neville, speaking as a lifelong supporter and former player, described the prospect of the final as unsettling.
"It is a huge game. The consequences are massive. I have a sickly feeling in my stomach about this game as a United fan purely because of what is at stake," he said, per BBC Sport.
While fellow pundit and ex-captain Roy Keane called it an exciting fixture, Neville took a more cautious view.
"Roy Keane called it a great game the other day," he said. "That is what Roy would think. My mentality is different. I was a right-back. You know the only thing you can do is lose your team the game. Unless you are Trent Alexander-Arnold, you are unlikely to win your team a game as a right-back. But I am confident. Manchester United have an uncanny knack, even in difficult times and bad times - and this has been a really bad season - of picking up trophies."