It took the Gunners just two minutes to break the deadlock as Chloe Kelly capitalised on Phallon Tullis-Joyce's error and scored the opening goal. The hosts' celebrations, however, were short-lived as Kelly's England team-mate Ella Toone equalised for United with a clinical header.
After an evenly contested first 45 minutes, an Arsenal barrage early in the second period ultimately settled the game. First, Grace Clinton tripped Caitlin Foord inside the United box and Mariona Caldentey scored her team's second goal from the spot in the 50th minute.
Six minutes later, Frida Maanum followed a through ball from Katie McCabe and found the back of the net to increase her team's lead, and just a minute past the hour mark, Kelly turned provider with an assist for Kim Little.
Just when it seemed that the north London side had taken an unassailable lead, the visitors staged a strong comeback. Elisabeth Terland intercepted a poor short pass from McCabe on the edge of the Arsenal box and pulled one back for the Red Devils in the 70th minute. McCabe then committed yet another mistake as her poorly-timed challenge on Celin Bizet led to United winning a penalty and Maya Le Tissier further reducing the gap.
Arsenal eventually survived the late scare as they secured crucial three points and sealed a second-placed finish at the end of the 2024-25 Women's Super League campaign. The final standings mean the Gunners will have a longer summer break and shorter pathway in Champions League qualifying.