Thursday's match up between Manchester United and Southampton at Old Trafford will wrap up matchday 21 of the Premier League.
Although both sides registered FA Cup wins over the weekend, Ruben Amorim's side are winless for four straight league games, while the Saints have not had a league win for 11 games on the trot.
Way off the European spots, United have 23 points from 20 games, while Ivan Juric's men are rooted to the bottom with just six from as many outings.
Here, GOAL brings you everything you need to know about how to watch, including TV channel, streaming details and more.
How to watch Manchester United vs Southampton online - TV channels & live streams
In the United Kingdom (UK), the Premier League match between Manchester United and Southampton will be available to watch and stream online live through TNT Sports 1 and TNT Sports Ultimate.
Check out GOAL's Live Match Centre for updates.
How to watch anywhere with VPN
If you are abroad, you may need to use a virtual private network (VPN) in order to watch games using your usual streaming service. A VPN, such as NordVPN, allows you to establish a secure connection online when streaming. If you are not sure which VPN to use, check out GOAL's guide to the best VPNs for streaming sport.
Manchester United vs Southampton kick-off time
The Premier League match between Manchester United and Southampton will be played at Old Trafford in Manchester, England.
It will kick off at 8 pm GMT on Thursday, January 16, in the UK.
Team news & squads
Manchester United team news
While Luke Shaw, Mason Mount, Victor Lindelof and Jonny Evans continue to nurse their injuries, Marcus Rashford remains uncertain over his future at the club.
Diogo Dalot will serve a one-match ban after picking two bookings against Arsenal on Sunday, so Tyrell Malacia would see himself operate on the left side with either Noussair Mazraoui or Amad Diallo on the right.
Leny Yoro will have his task cut out against Matthijs de Ligt and Harry Maguire, while Joshua Zirkzee could get the nod ahead of Rasmus Hojlund.
Southampton team news
Juric is sweating on the availability of Flynn Downes after the midfielder missed the last three games with a thigh problem, but trio Jack Stephens, Juan Larios and Ross Stewart are sure to miss out due to injuries.
Will Smallbone is in contention after returning from injury as a substitute over the weekend, while Aaron Ramsdale is set to reclaim the gloves from Gavin Bazunu in goal.
Meanwhile, Matheus Fernandes is back from his ban to feature in the middle, with the United-linked Tyler Dibling, Kamaldeen Sulemana, Paul Onuachu, Cameron Archer and Adam Armstrong all battling for a spot in attack.