Having grown used to upsetting the odds over the last couple of seasons, Leicester City will need to defy expectations once again if they are to leave the Vicente Calderon with anything to cheer about on Wednesday evening.
With Atletico Madrid having kept a clean sheet in 15 of their last 17 Champions league home games, the Foxes are up against it to find that all-important away goal in the Spanish capital.
However, having hit the back of the net away to Sevilla in the last round, Jamie Vardy is his side’s 11/1 (12.00) favourite with dabblebet to open the scoring in another game on Spanish soil, and on offer at 10/3 (4.33) to strike anytime for the seventh time in nine club appearances.
On the scoresheet for the second game in succession in Sunday’s 4-2 defeat at Everton, Islam Slimani is priced at 15/4 (4.75) to make it three in a row in style, while his Algerian compatriot Riyad Mahrez can be backed at 5/1 (6.00) to score a fifth goal in this season’s competition.
At the other end of the pitch, Antoine Griezmann will be looking to follow up his late equaliser in the derby against Real Madrid by firing the Colchoneros en route to a third semi-final appearance in four seasons.
With 11 goals to his name the last 21 Champions League games, the France international is a clear 17/20 (1.85) favourite to break the deadlock and on offer at just 4/6 (1.67) to strike anytime.
Picked in the place of the injured Kevin Gameiro at 17/20 (1.85) for the Madrid derby, Fernando Torres is available at 21/20 (2.05) to score for the first time since he grabbed the fourth in a 4-2 away win over Bayer Leverkusen in the last round back in February.
However, better value may be found in backing Yannick Ferreira Carrasco at 6/4 (2.50) to add to his 12 goals for the season so far, with the Belgium international currently enjoying his most prolific ever season in professional football.