GOAL6 predictions: Win £100,000 in our new free-to-play game as we back Man Utd to send Ruud van Nistelrooy packing & Liverpool to ease past Plymouth in FA Cup

Team news

Lisandro Martinez's season-ending knee injury will see changes at the back for Manchester United, with Matthijs de Ligt the obvious replacement for the Argentine. With Ruben Amorim's experiment of playing Kobbie Mainoo in a No.9 role having backfired in the defeat to Crystal Palace last time out, one of Rasmus Hojlund or Joshua Zirkzee is likely to be recalled to the starting XI.

New signing Patrick Dorgu, meanwhile, could make his debut. As for Leicester, they'll be looking to bounce back from the 4-0 hammering at the hands of Everton, with Ruud van Nistelrooy likely to ring the changes at Old Trafford.

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Form

Man Utd: L W W W L

Leicester: L W L L W

Our GOAL6 prediction

Man Utd 3-1 Leicester City

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Last three meetings

Team news

Torn apart by Arsenal in their last fixture, Manchester City will be desperate to avoid an embarrassing FA Cup exit at the hands of League One side Leyton Orient when they travel to Brisbane Road on Saturday. Pep Guardiola is unlikely to rest many of his big names to make sure they get the job done, although the likes of Jack Grealish, Rico Lewis and James McAtee could well be brought into the starting XI having seen their minutes dry up at the start of 2025.

Abdukodir Khusanov is another who could come in, having not played since his nightmare debut in the win over Chelsea, while another January signing, Vitor Reis, could make his first appearance for the club. Deadline-day arrival from Porto, Nico Gonzalez, is also in contention to make the matchday squad.

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Form

Leyton Orient: L W W L D

Man City: L W W L W

Our GOAL6 prediction

Leyton Orient 0-4 Man City

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Last three meetings

Team news

David Moyes has revitalised Everton since his return as manager in January, with the Toffees having now won three on the spin. Despite Premier League survival undoubtedly being the priority, it's unlikely the Scot will want to make wholesale changes to disrupt his team's momentum, with there being the possibility he'll keep the same starting XI from the impressive 4-0 win over Leicester.

Youssef Chermiti (thigh) and Dwight McNeil (knee) remain sidelined, while Dominic Calvert-Lewin and Armando Broja are also out. Deadline-day signing Carlos Alcaraz, meanwhile, will be hoping to make his debut. As for Bournemouth, Eli Junior Kroupi, the January signing from FC Lorient, will hope to make the matchday squad, while Luis Sinisterra could well make his return following an injury lay-off.

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Form

Everton: W W W L W

Bournemouth: L W W D W

Our GOAL6 prediction

Everton 1-1 Bournemouth

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Last three meetings

Team news

Brighton will know they need to drastically improve their performance levels after their embarrassing 7-0 loss at the hands of title-chasing Nottingham Forest, with under-pressure Fabian Hurzeler likely to ring the changes for the FA Cup tie with Chelsea. To that end, Simon Adingra and Matt O'Riley will both be pushing for starts after being benched at the City Ground, while Diego Gomez could make his full debut.

For the visitors, Enzo Maresca's line-up will give an indication as to how seriously he views FA Cup glory this season, with many of his squad players needing minutes. Indeed, the likes of Christopher Nkunku and Pedro Neto only started on the bench in the win over West Ham and should come back in, while Robert Sanchez and Trevoh Chalobah could also earn recalls.

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Form

Brighton: L L W W W

Chelsea: W L W D W

Our GOAL6 prediction

Brighton 0-2 Chelsea

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Last three meetings

Team news

Depending on their involvement in Thursday's Carabao Cup semi-final second leg against Tottenham, Federico Chiesa and Joe Gomez should both start in Sunday's FA Cup fixture, given their lack of involvement in Premier League matches to date. Arne Slot may decide to rest some of his big names entirely, with the likes of Mohamed Salah and Virgil van Dijk having been given the day off in the previous round, a comfortable 4-0 win over Accrington Stanley.

That game did see a debut for talented 16-year-old forward Rio Ngumoha, and he'll be hoping to be involved again when the Reds make the trip to Home Park to face the Championship strugglers, who are coming off the back of a positive 2-1 victory over West Brom.

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Form

Plymouth: W D L L D

Liverpool: W L W W W

Our GOAL6 prediction

Plymouth 0-3 Liverpool

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Last three meetings

Team news

Marcus Rashford and Marco Asensio will both be pushing to make their Aston Villa debuts following January loan moves from Manchester United and PSG respectively, although Axel Disasi is cup-tied and will have to wait for his Villa bow. Donyell Malen, meanwhile, is likely to feature again, with doubts remaining over Ollie Watkins following the muscle issue he suffered in the 2-0 loss to Wolves.

Elsewhere, Tyrone Mings isn't expected to be ready to return, while Matty Cash is out with a long-term injury. As for Tottenham, much will depend on the outcome of their Carabao Cup semi-final second leg meeting with Liverpool, with new signings Kevin Danso and Mathys Tel in contention to play.

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Form

Aston Villa: L W D L D

Tottenham: W W L W L

Our GOAL6 prediction

Aston Villa 2-1 Tottenham

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Last three meetings