Inter Miami are heavy favorites for MLS Cup 2025, LAFC a distant second according to Las Vegas Sportsbook

Las Vegas sees Inter Miami CF as the clear favorite to claim the 2025 MLS Cup title. The David Beckham-owned team, led by global superstar Lionel Messi, tops the list with odds of +370. LAFC follows in second place, while LA Galaxy, despite being the reigning champions after defeating the New York Red Bulls in the 2024 MLS Cup final, sit in third.

One of the most surprising placements is San Diego FC, the league’s newest expansion team debuting in 2025. The 30th team in MLS is ranked 25th with +6500 odds to win it all. Odds courtesy of DraftKings Sportsbook.

Inter Miami's status as the MLS Cup frontrunner highlights Lionel Messi's transformative impact since his arrival at the side. The odds reflect bookmakers' belief in Miami's potential.

As the 2025 MLS season approaches, all eyes will be on Inter Miami CF to see if they can live up to the high expectations set by oddsmakers. The Herons have already kicked off their 2025 season with a 1-0 win over Sporting KC in the First Leg of their Round 1 CONCACAF Champions Cup clash. They host New York City FC in their 2025 MLS opener at the Chase Stadium before welcoming Sporting KC to Miami for the second leg of their CONCACAF Champions Cup matchup.