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The Chicago Cubs are set to host the St. Louis Cardinals to open the pivotal three-game series on September 26, 2025, at 2:20 pm ET/11:20 am PT.
Chicago is eighth with an average of 4.86 runs per game, while the Cardinals are in 18th place with an average of 4.31 runs per game. Additionally, St. Louis is rated 17th with a hitting average of .246, while the Cubs are slightly ahead at 14th place with an average of .249.
Chicago leads in on-base percentage as well, ranking 11th with .320, while the Cardinals are not far behind at 14th with .316. The Cubs are ranked seventh with a slugging percentage of.427, while the Cardinals are placed 27th with a slugging percentage of .380.
Here, GOAL brings you everything you need to know about how to watch Chicago Cubs vs St. Louis Cardinals MLB game, plus plenty more.
How to watch Chicago Cubs vs St. Louis Cardinals on TV & stream live online
National TV channel: MLBN
Streaming service: Fubo
To watch the entire MLB season, Fubo and DirecTV Stream are the two best streaming services for baseball fans. Both carry MLB.tv for out-of-market access to games and you can also check out our table below for information on regional sports networks and where to find them.
READ MORE:FuboTV Review: Pricing, plans, subscriptions, free trials and more
| Team | Local Network | Streaming Providers |
|---|---|---|
| Arizona Diamondbacks | DBACKS.tv | Fubo, DirecTV Stream |
| Atlanta Braves | FanDuel Sorts Network South | Fubo, DirecTV Stream |
| Baltimore Orioles | Mid-Atlantic Sports Network | Fubo, DirecTV Stream |
| Boston Red Sox | New England Sports Network | Fubo, DirecTV Stream, NESN 360 |
| Chicago Cubs | Marquee Sports Network | Fubo, DirecTV Stream |
| Chicago White Sox | NBC Sports Chicago | Fubo, DirecTV Stream |
| Cincinnati Reds | FanDuel Sports Network Ohio | Fubo, DirecTV Stream |
| Cleveland Guardians | FanDuel Sports Network Great Lakes | Fubo, DirecTV Stream |
| Colorado Rockies | ROCKIES.tv | DirecTV Stream |
| Detroit Tigers | FanDuel Sorts Network Detroit | Fubo, DirecTV Stream, FanDuel+ |
| Houston Astros | Space City Home Network | Fubo, DirecTV Stream |
| Kansas City Royals | FanDuel Sports Network Kansas City | Fubo, DirecTV Stream, FanDuel+ |
| Los Angeles Angels | FanDuel Sports Network West | Fubo, DirecTV Stream |
| Los Angeles Dodgers | SportsNet Los Angeles | DirecTV Stream |
| Miami Marlins | FanDuel Sports Network Florida | Fubo, DirecTV Stream, FanDuel+ |
| Milwaukee Brewers | FanDuel Sports Network Wisconsin | Fubo, DirecTV Stream, FanDuel+ |
| Minnesota Twins | FanDuel Sports Network North | Fubo, DirecTV Stream |
| New York Mets | SportsNet New York | Fubo, DirecTV Stream |
| New York Yankees | YES Network | Fubo, DirecTV Stream |
| Oakland Athletics | NBC Sports California | Fubo, DirecTV Stream |
| Philadelphia Phillies | NBC Sports Philadelphia | Fubo |
| Pittsburgh Pirates | SportsNet Pittsburgh | Fubo, DirecTV Stream |
| San Diego Padres | Padres.TV | Fubo, DirecTV Stream |
| San Francisco Giants | NBC Sports Bay Area | Fubo, DirecTV Stream |
| Seattle Mariners | ROOT Sports | Fubo, DirecTV Stream |
| St Louis Cardinals | FanDuel Sports Network Midwest | Fubo, DirecTV Stream |
| Tampa Bay Rays | FanDuel Sports Network Sun | Fubo, DirecTV Stream, FanDuel+ |
| Texas Rangers | FanDuel Sports Network Southwest | Fubo, DirecTV Stream |
| Toronto Blue Jays | Sportnet (Canada) | N/A |
| Washington Nationals | Mid-Atlantic Sports Network | Fubo, DirecTV Stream |
Chicago Cubs vs St. Louis Cardinals: Date and First-Pitch Time
The Chicago Cubs are set to host the St. Louis Cardinals to open the pivotal three-game series on September 26, 2025, at 2:20 pm ET/11:20 am PT at Wrigley Field in Chicago, Illinois.
| Date | September 26, 2025 |
| First-Pitch Time | 2:20 pm ET/11:20 am PT |
| Venue | Wrigley Field |
| Location | Chicago, Illinois |
Streaming the game with a VPN
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Chicago Cubs vs St. Louis Cardinals team news
Chicago Cubs team news
Michael Busch has 31 home runs, a .255 batting average, and 84 RBIs.
Nico Hoerner has a .299 batting average, .348 on-base percentage, and .393 slugging percentage.
Seiya Suzuki has a batting average of .244 and has driven in 97 RBIs with 29 home runs.
Chicago Cubs injury report
| Player | Position | Injury | Injury Status |
|---|---|---|---|
| Cade Horton | SP | Back injury | Day-to-Day |
| Miguel Amaya | C | Left ankle sprain | Out, 10-Day IL |
St. Louis Cardinals team news
Willson Contreras has scored 80 RBIs, 20 home runs, and a .257 batting average.
Alec Burleson has been hitting .293 with a slugging percentage of .464 and an on-base percentage of .345.
Kyle Leahy has a 4-2 record and a 3.18 ERA.
St. Louis Cardinals injury report
| Player | Position | Injury | Injury Status |
|---|---|---|---|
| Willson Contreras | INF | Right shoulder strain | Out, 10-Day IL |
| Masyn Winn | SS | Right knee injury | Out, 10-Day IL |
Chicago Cubs and St. Louis Cardinals projected starting pitchers
| Date | Chicago Cubs | St. Louis Cardinals |
|---|---|---|
| September 26, 2025 | Colin Rea | Miles Mikolas |
| September 27, 2025 | Javier Assad | Michael McGreevy |
| September 28, 2025 | Jameson Taillon | TBD |
Chicago Cubs and St. Louis Cardinals head-to-head record
The outcomes of the last five meetings between the Chicago Cubs and the St. Louis Cardinals indicate a back-and-forth contest in which no side has a clear advantage. The Cubs demonstrated their capacity to score runs rapidly with two strong offensive performances, winning 9-1 on August 10, 2025, and 11-0 on July 7, 2025.
The Cardinals, on the other hand, responded with three convincing wins, including a close 3-2 triumph on August 11, a shutout 5-0 victory on August 9, and a thrilling 8-6 victory on July 5, demonstrating their ability to outslug and outpitch the Cubs.
This game might go any way because both teams have been able to trade momentum and produce convincing victories. The difference will probably come down to pitching consistency and whichever lineup settles into a groove first.
| Date | Results |
|---|---|
| Aug 11, 2025 | Cardinals 3-2 Cubs |
| Aug 10, 2025 | Cubs 9-1 Cardinals |
| Aug 09, 2025 | Cardinals 5-0 Cubs |
| Jul 07, 2025 | Cubs 11-0 Cardinals |
| Jul 05, 2025 | Cardinals 8-6 Cubs |