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The Houston Astros are set to face the Seattle Mariners to start the highly anticipated third game of their three-game series on September 21, 2025, at 7:10 pm ET/4:10 pm PT. The Mariners shut out the Astros 4-0 in the opening game of the current three-game series.
The Mariners rank higher at 11th with 4.73 runs per game, while the Astros average 4.23 runs per game, which places them in 24th spot. Seattle is in 20th place with a batting average of .244, while Houston is in ninth place with a .251 at the plate.
The Mariners have a little lead with a .320 on-base percentage, which places them in the tenth spot, just ahead of the Astros' .317 on-base percentage, which ranks fourteenth. Seattle leads once more, finishing 10th with a .420 slugging percentage, followed by Houston in 16th place with a .398 slugging percentage.
Here, GOAL brings you everything you need to know about how to watch Houston Astros vs Seattle Mariners MLB game, plus plenty more.
How to watch Houston Astros vs Seattle Mariners on TV & stream live online
National TV channel: ESPN
Streaming service: Fubo
To watch the entire MLB season, Fubo and DirecTV Stream are the two best streaming services for baseball fans. Both carry MLB.tv for out-of-market access to games and you can also check out our table below for information on regional sports networks and where to find them.
READ MORE:FuboTV Review: Pricing, plans, subscriptions, free trials and more
| Team | Local Network | Streaming Providers |
|---|---|---|
| Arizona Diamondbacks | DBACKS.tv | Fubo, DirecTV Stream |
| Atlanta Braves | FanDuel Sorts Network South | Fubo, DirecTV Stream |
| Baltimore Orioles | Mid-Atlantic Sports Network | Fubo, DirecTV Stream |
| Boston Red Sox | New England Sports Network | Fubo, DirecTV Stream, NESN 360 |
| Chicago Cubs | Marquee Sports Network | Fubo, DirecTV Stream |
| Chicago White Sox | NBC Sports Chicago | Fubo, DirecTV Stream |
| Cincinnati Reds | FanDuel Sports Network Ohio | Fubo, DirecTV Stream |
| Cleveland Guardians | FanDuel Sports Network Great Lakes | Fubo, DirecTV Stream |
| Colorado Rockies | ROCKIES.tv | DirecTV Stream |
| Detroit Tigers | FanDuel Sorts Network Detroit | Fubo, DirecTV Stream, FanDuel+ |
| Houston Astros | Space City Home Network | Fubo, DirecTV Stream |
| Kansas City Royals | FanDuel Sports Network Kansas City | Fubo, DirecTV Stream, FanDuel+ |
| Los Angeles Angels | FanDuel Sports Network West | Fubo, DirecTV Stream |
| Los Angeles Dodgers | SportsNet Los Angeles | DirecTV Stream |
| Miami Marlins | FanDuel Sports Network Florida | Fubo, DirecTV Stream, FanDuel+ |
| Milwaukee Brewers | FanDuel Sports Network Wisconsin | Fubo, DirecTV Stream, FanDuel+ |
| Minnesota Twins | FanDuel Sports Network North | Fubo, DirecTV Stream |
| New York Mets | SportsNet New York | Fubo, DirecTV Stream |
| New York Yankees | YES Network | Fubo, DirecTV Stream |
| Oakland Athletics | NBC Sports California | Fubo, DirecTV Stream |
| Philadelphia Phillies | NBC Sports Philadelphia | Fubo |
| Pittsburgh Pirates | SportsNet Pittsburgh | Fubo, DirecTV Stream |
| San Diego Padres | Padres.TV | Fubo, DirecTV Stream |
| San Francisco Giants | NBC Sports Bay Area | Fubo, DirecTV Stream |
| Seattle Mariners | ROOT Sports | Fubo, DirecTV Stream |
| St Louis Cardinals | FanDuel Sports Network Midwest | Fubo, DirecTV Stream |
| Tampa Bay Rays | FanDuel Sports Network Sun | Fubo, DirecTV Stream, FanDuel+ |
| Texas Rangers | FanDuel Sports Network Southwest | Fubo, DirecTV Stream |
| Toronto Blue Jays | Sportnet (Canada) | N/A |
| Washington Nationals | Mid-Atlantic Sports Network | Fubo, DirecTV Stream |
Houston Astros vs Seattle Mariners: Date and First-Pitch Time
The Houston Astros and the Seattle Mariners will meet in an electrifying MLB game on September 21, 2025, at 7:10 pm ET/4:10 pm PT at Daikin Park in Houston, Texas.
| Date | September 21, 2025 |
| First-Pitch Time | 7:10 pm ET/4:10 pm PT |
| Venue | Daikin Park |
| Location | Houston, Texas |
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Houston Astros vs Seattle Mariners team news
Houston Astros team news
Jose Altuve has contributed 74 RBIs, a batting average of .261, and 26 home runs.
Jeremy Pena is hitting .303 with a .361 on-base percentage and a .470 slugging percentage.
Christian Walker has a .233 batting average, 23 home runs, and 82 RBIs.
Houston Astros injury report
| Player | Position | Injury | Injury Status |
|---|---|---|---|
| Yordan Alvarez | LF | Left ankle sprain | Out, 10-Day IL |
| Josh Hader | RP | Left shoulder strain | Out, 15-Day IL |
Seattle Mariners team news
Cal Raleigh has 56 home runs, a .246 batting average, and 118 RBI.
Julio Rodríguez is hitting .269 with a .321 on-base percentage and a .479 slugging percentage.
Eduard Bazardo has a 5-0 record and a 2.36 ERA.
Seattle Mariners injury report
| Player | Position | Injury | Injury Status |
|---|---|---|---|
| Jackson Kowar | RP | Right shoulder impingement | Out, 15-Day IL |
| Logan Evans | SP | Right elbow inflammation | Out, 15-Day IL |
Houston Astros and Seattle Mariners projected starting pitchers
| Date | Houston Astros | Seattle Mariners |
|---|---|---|
| September 19, 2025 | Hunter Brown | Bryan Woo |
| September 20, 2025 | Framber Valdez | George Kirby |
| September 21, 2025 | Jason Alexander | Logan Gilbert |
Houston Astros and Seattle Mariners head-to-head record
The series has been very well matched, with momentum going both ways in the last five meetings between the Houston Astros and the Seattle Mariners. The Mariners recently defeated the Astros 4-0 on September 20, 2025. They had previously won 7–6 in a thrilling game on July 20 and 6–1 on July 19.
However, the Astros have also had their explosive moments, such as their 5-3 victory on May 25 and their 11-3 victory on July 21.
The Mariners have demonstrated the ability to handle the Astros' offense and win games that are controlled or low-scoring, but these results indicate that Houston's bats can overwhelm Seattle when they are at their strongest. This pattern suggests that the outcome of the next game may depend on whether Seattle's pitching silences them or if the Astros' offense makes an early breakthrough.
| Date | Results |
|---|---|
| Sep 20, 2025 | Mariners 4-0 Astros |
| Jul 21, 2025 | Astros 11-3 Mariners |
| Jul 20, 2025 | Mariners 7-6 Astros |
| Jul 19, 2025 | Mariners 6-1 Astros |
| May 25, 2025 | Astros 5-3 Mariners |