Sevilla team news
Gonzalo Montiel is suspended after to the booking at Old Trafford. Former Manchester City wide player Jesus Navas, who started in the Valencia win, is the likely replacement.
Among the eight changes made in the last league game, Ivan Rakitic, Oliver Torres, Tanguy Nianzou and goalkeeper Bono should return to the XI, but Mendilibar may look to try out Youssef En-Nesyri ahead of Erik Lamela up front.
Pape Gueye and Tecatito are ineligible to play here, while Marcus Acuna and Alex Telles are back from domestic bans, although the on-loan United full-back may start on the bench again.
Sevilla possible XI: Bono; Navas, Nianzou, Marcao, Acuna; Fernando, Gudelj; Ocampos, Rakitic, Torres; En-Nesyri
| Position | Players |
|---|
| Goalkeepers | Bono, Dmitrovic |
| Defenders | Marcao, Bade, Nianzou, Rekik, Telles, Acuna, Navas |
| Midfielders | Gudelj, Fernando, Jordan, Torres, Rakitic, Gomez |
| Forwards | Ocampos, Suso, En-Nesyri, Mir, Lamela, Gil |
Manchester United team news
Bruno Fernandes' booking in the first leg means he is suspended, while Donny van de Beek, Alejandro Garnacho, Tom Heaton, Lisandro Martinez and Raphael Varane make up for the injuries at the club.
Marcus Rashford has returned to training and could feature in Spain, but Luke Shaw, Tyrell Malacia, Scott McTominay and Marcel Sabitzer remain doubts.
Given the potential absentees, Fred is likely to join Christian Eriksen and Casemiro in the middle, with Harry Maguire and Victor Lindelof at the heart of the defence.
Should Rashford be named in the squad, it may be on the bench, with Anthony Martial supported in attack by Jadon Sancho and Antony.
Manchester United possible XI: De Gea; Wan-Bissaka, Maguire, Lindelof, Shaw; Casemiro, Fred, Eriksen; Antony, Martial, Sancho
| Position | Players |
|---|
| Goalkeepers | De Gea, Butland |
| Defenders | Maguire, Lindelof, Jones, Shaw, Malacia, Williams, Dalot, Wan-Bissaka |
| Midfielders | Casemiro, McTominay, Eriksen, Sabitzer, Fred, Pellistri |
| Forwards | Rashford, Elanga, Antony, Sancho, Martial, Weghorst |
Head-to-head record
| Date | Result | Competition |
|---|
| April 14, 2023 | Manchester United 2-2 Sevilla | Europa League |
| August 17, 2020 | Sevilla 2-1 Manchester United | Europa League |
| March 14, 2018 | Manchester United 1-2 Sevilla | Champions League |
| February 22, 2018 | Sevilla 0-0 Manchester United | Champions League |
| August 12, 2013 | Manchester United 1-3 Sevilla | Club friendly |
