Real Madrid begin their Copa Del Rey campaign on Tuesday evening with Carlo Ancelotti's men facing a trip to fourth tier Cacereno.
While Los Blancos have numerous league and European titles over the last few years, Spain's domestic cup competition has proved elusive for them with their triumphs in 2011 and 2014 the only time they have lifted the trophy in the last 30 years.
Cacereno vs Real Madrid latest odds
The hosts claimed a La Liga scalp in the previous round beating Girona 2-1, but Cacereno remain rank outsiders at 18/1 (19.00) with bet365 to beat the most successful side in Spanish football history.
Madrid meanwhile are priced at 1/9 (1.11) to win in 90 minutes while the game is priced at 7/1 (8.00) to go to extra time.
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Cacereno vs Real Madrid first goal scorer odds
First goal scorer odds are not available for this game.
Cacereno vs Real Madrid preview
Madrid will naturally make changes to the starting eleven given the hectic schedule which awaits them over the next two months and the side which lines up on Tuesday evening is likely to bear little resemblance to the one which won at Valladolid in La Liga on Friday.
Players like Eden Hazard, Nacho Fernandez, Dani Ceballos and Lucas Vazquez may not be regulars in the Madrid side but all are international players capable of helping Madrid to a victory.
Opposing a high scoring game however should be of interest and this looks like it will be a match where Los Blancos will get the job done rather than blow away the opposition.
Cacereno vs Real Madrid tips and predictions
Under 3.5 goals has paid out in six of Madrid's last eight away games in all competitions and is priced at 8/11 (1.73).
Combining this selection with a Real Madrid victory sees the odds rise to 11/10 (2.10) which looks like a tempting option.
Odds correct at the time of writing. Please gamble responsibly.