Having already made two outings in the cup competition, the Ghana international is all but set to make it three in the semi-final fixture to be played at the Juventus Stadium.
The utility man has 10 league outings to his name thus far, with two further games in the Champions League.
“[Daniele] Rugani will be rested,” Allegri told pressmen in his team news.
“I’ve [Leonardo] Bonucci, [Andrea] Barzagli, [Mehdi] Benatia and [Giorgio] Chiellini all at my disposal and I’ll decide later who will start against Napoli.
“[Stephan] Lichtsteiner and Asamoah will occupy the full-back slots, while in goal, Neto starts again. He’s a great keeper and he’s only a deputy to [Gianluigi] Buffon because it’s Buffon!
“I’ve several midfielders vying for starting berths. Regarding the forwards, [Paulo] Dybala played well on Saturday. He’s essential in linking midfield and attack, and he raises the technical level of the whole team which is very important.
“[Gonzalo] Higuain is a player who needs to be on the pitch more often than not because that helps keep in peak condition. I’ll make a call later on [Marko] Pjaca’s involvement.”
Gradually, Asamoah seems to be getting back to his feet after enduring a frustrating time between 2014 and 2016.
A knee problem warranted surgery in December 2014, and the Accra-born has since experienced a series of relapses - one that limited him to 18 league appearances in seasons 2014-15 and 2015-16 combined.
He opted out of the recent Africa Cup of Nations in Gabon, with an intention to focus solely on club football on his road to full recovery.