Real Madrid will be hoping to bounce back this weekend from their disastrous Copa del Rey exit to Leganes on Wednesday evening.
Los Blancos were beaten 2-1 at the Bernabeu to further increase the pressure on Zinedine Zidane and his players, whilst Valencia beat Alaves on penalties.
Los Che sit five points clear of Madrid in La Liga and they will be aiming to extend that gap on Saturday afternoon.
Match odds
dabblebet offer an eighth home league win of the season for Valencia at 15/4 (4.75), while Madrid can be backed at 4/6 (1.66). The draw is offered at 7/2 (4.50).
Watch and bet live on Valencia v Real Madrid
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Team news
Sergio Ramos and Karim Benzema made their first starts of the year against Leganes after returning from injury, and both are in contention to start at Mestalla.
Valencia have problems in defence with Ruben Vezo and Gabriel Paulista both suspended, while Jeison Murillo remains injured.
Goals to flow

While Madrid are going through a difficult period, Valencia too have seen their form drop off recently.
Los Che have lost three of their last five league games and have failed to keep a clean sheet in any of their last eight La Liga encounters.
Madrid, for their part, have only kept clean sheets in three of their eight away matches, and with their confidence at a low ebb, Valencia will feel they can certainly get among the goals.
Tips and predictions
Both teams to score and either to win is offered at an appealing 17/20 (1.85). This bet has paid out in five of Valencia's last six league games and in four of Madrid's last seven games on the road.
Both teams to score and either to win at 17/20 (1.85) for a 2.5pt stake with dabblebet
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