Facing a 4-0 deficit from last month's first leg in Switzerland, Basel require a footballing miracle if they are to knock Manchester City out of the Champions League.
Pep Guardiola's side have established what appears to be an insurmountable advantage in the tie and they will surely secure a place in the quarter finals of the competition.
Latest odds
City have not lost a home match since December 2016, while they have have won 10 of their last 13 Champions League matches on their own patch.
As such, it is unsurprising that SportPesa make them a 2/17 (1.12) chance to win Wednesday's second leg, while the same firm go 33/4 (9.25) that the tie remains level at the end of 90 minutes.
Basel are playing for pride and they are chalked up as a 24/1 (25.0) shot to win the second leg against Guardiola's men.
Team news
Gabriel Jesus could start this clash for the home side as he completes his recovery, affording Sergio Aguero a rare breather.
Fabian Delph is available for selection after missing City's last three games due to suspension.
Basel duo Eder Balanta and Germano Vailati both face late fitness tests ahead of Tuesday's clash.
City set to cruise?
Manchester City have kept a clean sheet in four of their last six victories in this competition and SportPesa go 5/7 (1.71) that Guardiola's team win to nil here.
The price of 8/5 (2.60) that the home side score at least two first half goals also appeals - City scored three times inside the opening 23 minutes during the first leg at St Jakob-Park.
Preview and predictions
Better value, though, could lie in backing the home side to get amongst the goals again when they face Raphael Wicky's side.
City have won by three or more clear goals in five of their last six victories and SportPesa's 6/5 (2.20) quote for the trend to continue could offer good value for punters ahead of Wednesday's tie.
Manchester City (-2) at 6/5 (2.20) for a 1pt stake with SportPesa