There is a record-high 10 MLS teams competing in 2025, including FC Cincinnati, Inter Miami CF, LA Galaxy, Real Salt Lake, Sporting Kansas City, Seattle Sounders, Colorado Rapids, Columbus Crew, LAFC and the Vancouver Whitecaps. However, multiple MLS sides will exit after the opening round due to domestic matchups, meaning only a few will truly compete for the coveted prize. Among them, three truly stand out, and GOAL details them below.
LA Galaxy:
MLS' reigning champions blew the league away in 2024, claiming their first MLS Cup since 2014. The quartet of Gabriel Pec, Joseph Paintsil, Riqui Puig, and Dejan Joveljic dominated defenses in the league, week after week. However, Joveljic has since departed, after Sporting KC acquired him for $4M, which ultimately means big changes for the club. Then LA also have to factor the absence of Puig, who is still recovering from the injury he got in the Western Conference Final.
They have yet to fill Joveljic's spot on the roster, or a solution in Puig's absence, which could mean their attack doesn't quite click in the same fashion. However, with an automatic berth into the Round of 16, they're still ultimately one of MLS' favorites.
Inter Miami:
Simply having Lionel Messi on your roster ultimately gives you a leg up over your opposition. Simply put, he is a game-changing attacker in any situation, and if healthy, he will be an incredible asset for the Herons during their 2025 CCC run. The competition will also prove to be a good challenge for the club ahead of the 2025 FIFA World Cup, which begins shortly after the 2025 CCC final.
In Round 1, Miami clashes with Sporting Kansas City in a two-legged affair.
Columbus Crew:
One thing is certain about this team: they are resilient. True fighters, the Crew's 2024 run in CCC was remarkable, and they followed it up by winning the Leagues Cup and clinching the second spot in the Eastern Conference playoffs. Although their postseason run was underwhelming, Nancy's men are still one of the favorites heading into the 2025 edition of the tournament, and like the Galaxy, have a Round 1 bye and will enter come the Round of 16. Despite the rumored exit of Cucho Hernandez, Nancy is MLS's top coach for a reason and he will likely have a solution in place by the time his team takes the pitch for its CCC match-up.