Eventi chiave
NSC
MIA- 2 - 1
- H. Neville
Cartellino giallo
- D. Arroyo
Cartellino giallo
- L. MacNaughton
S. Moore
2 - 0 - F. Picault
H. Mukhtar
1 - 0
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Est
| Pos | Squadra | G | V | P | S | GF | GS | +/- | Pt. | Forma | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  Nashville SC | 30 | 20 | 7 | 3 | 64 | 23 | 41 | 67 |
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| 2 |  Inter Miami CF | 30 | 15 | 10 | 5 | 73 | 51 | 22 | 55 |
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| 3 |  New England Revolution | 30 | 16 | 4 | 10 | 49 | 41 | 8 | 52 |
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| 4 |  Chicago Fire FC | 30 | 14 | 6 | 10 | 52 | 44 | 8 | 48 |
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| 5 |  Charlotte FC | 30 | 13 | 8 | 9 | 53 | 45 | 8 | 47 |
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| 6 |  Philadelphia Union | 30 | 13 | 7 | 10 | 61 | 48 | 13 | 46 |
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