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Southampton vs Arsenal Predictions: EPL Matchweek 13 Best Bets

Southampton (3-2-6) will host Mikel Arteta and the Gunners (9-0-1) this weekend in a Premier League clash at Saint Mary’s Stadium.

Arsenal currently sits at the top of the EPL table, four points clear of Manchester City. The Gunners are fresh off a 1-0 victory in the Europa League on Thursday and have won their last four matches in the Premier League.

Meanwhile, the Saints have lost three of their last five. However, they are on the heels of a 1-0 road victory against Bournemouth.

Will Arsenal keep their hot streak alive against Southampton? Or will the Saints play spoiler in front of their home crowd?

Let’s look at current betting lines to determine best bets and props for this Matchweek 13 Premier League showdown.

Matthew Williams' 2022-23 EPL Betting Record: 38-22 (+33.3 units)

Southampton vs Arsenal Odds

  • 3-Way Handicap: Southampton (+425) | Draw (+320) | Arsenal (-175)
  • Draw No Bet: Southampton (+290) | Arsenal (-450)
  • Over/Under Goals: Over 2.5 (-160) | Under 2.5 (+115)

Southampton vs Arsenal odds are current as of Thursday, Oct. 20, from BetMGM Sportsbook unless otherwise noted.

BetMGM has Arsenal listed as a massive road favorite, which is hardly a surprise. There is a strong lean toward the Over in anticipation of a possible blowout, with a Draw only getting (+320) odds in a 3-way handicap.

Southampton vs Arsenal Prediction

Southampton 0-3 Arsenal

I expect Arsenal to overwhelm Southampton from start to finish. The Gunners' attack has been consistent all season long, while their defense ranks among the best in the Premier League in goals conceded.

Southampton likes to take chances when they have the ball. Unfortunately, the Saints carry the fourth-lowest possession percentage in the league at 42.9 percent, while Arsenal sits as the fourth-best at 56.6.

Look for the Gunners to dominate possession — especially in the attacking third — with tons of short passes from Gabriel Martinelli and Bukayo Saka. In addition, I expect Arsenal to earn plenty of corners and possibly score from a set piece during the match.

Southampton vs Arsenal Betting Tips

  • Arsenal have scored 16 goals from open play and five from set pieces.
  • Gabriel Jesus ranks seventh in the EPL with five goals.
  • Saka ranks third in the EPL with four assists, while Jesus and Granit Xhaka have three each.
  • Southampton’s Armel Bella-Kotchap leads the Premier League with 2.3 interceptions per game.

Southampton vs Arsenal Best Bets

➕ Arsenal Wins: Multiple Correct Score 0:1, 0:2, or 0:3 (+230) at BetMGM Sportsbook

WAGER: 1 Unit

Given the odds, there is not much profit in backing Arsenal for an outright victory. However, you can gamble on several different combination bets to make up the difference.

My favorite options would be for Arsenal to Win plus Over 2.5 Goals or to make a Multiple Correct Score wager. I chose to ride with the latter, and did so due to the higher profit potential.

I expect Arsenal to outright dominate, and while this bet does not cover a Southampton goal, I am willing to risk that in this match.

➕ Halftime/Fulltime: Arsenal/Arsenal (+140) at BetMGM Sportsbook

WAGER: 1 Unit

As mentioned above, I expect a one-sided match. Why not double-dip in the pool and throw an additional prop bet down on the Gunners?

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