There is a slim chance Rashford will be fit in time for Villa's penultimate game of the season against Tottenham, which could be moved from its current date of May 18, but he is ineligible for their final-day fixture at his parent club Man Utd on May 25.
DID YOU KNOW?
The 27-year-old faces further tests to determine the severity of the injury, but it is not thought that he will need surgery. Rashford will undergo his rehabilitation with his loan side rather than returning to Manchester, despite the end of the season looming large - perhaps hinting at a stay at Villa Park beyond the summer.
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WHAT UNAI EMERY SAID
Speaking in a press conference after the crushing FA Cup defeat to Palace, Villa head coach Unai Emery said: "He’s injured. He got injured this week and yesterday we did a test - it is his hamstring. We are going to try to test him each match but he’s injured and probably won’t be available for some weeks."
WHAT NEXT FOR MARCUS RASHFORD?
The untimely injury might complicate Rashford's future. Villa have a £40 million ($50m) option to sign him permanently from United but it remains to be seen whether they will take that up, despite the England international impressing with 10 goal involvements in 17 appearances. For now, his focus will be on getting fit for England's fixtures in June.