This fixture last season produced an instant classic as Betis earned a 4-3 win in a pulsating game at Camp Nou - with the scoring opener by Barca's summer signing Junior Firpo.
|Game||Barcelona vs Real Betis|
|Date||Sunday, August 25|
|Time||8:00pm BST / 3:00pm ET|
|Stream (US)||fubo TV (7-day free trial)|
TV Channel, Live Stream & How To Watch
In the United States (US), the game can be watched live and on-demand with fuboTV (7-day free trial) .
New users can sign up for a free seven-day trial of the live sports streaming service, which can be accessed via iOS, Android, Chromecast, Amazon Fire TV, Roku and Apple TV as well as on a web browser.
|US TV channel||Online stream|
|beIN Sports / beIN Sports en Espanol||fubo TV (7-day free trial)|
In the United Kingdom (UK), the match will be shown live on ITV 4, and available to stream on the ITV Hub.
|UK TV channel||Online stream|
|ITV 4||ITV Hub|
Squads & Team News
|Goalkeepers||Ter Stegen, Pena|
|Defenders||Pique, Lenglet, Semedo, Umtiti, Junior, Alba|
|Midfielders||Rakitic, Busquets, Arthur, Rafinha, Roberto, De Jong, Vidal|
|Forwards||Griezmann, Perez, Fati|
Barcelona starting XI: Ter Stegen; Semedo, Pique, Lenglet, Alba; Busquets, De Jong, Roberto; Perez, Griezmann, Rafinha.
|Position||Real Betis squad|
|Defenders||Francis, Feddal, Bartra, Sidnei, Moreno, Barragan, Emerson, Mandi|
|Midfielders||Garcia, Pedraza, Canales, Tello, Carvalho, Joaquin, Guardado, Lainez, Kaptoum, Narvaez|
|Forwards||Iglesias, Fekir, Juanmi, Loren|
Betis starting XI: Martin; Emerson, Bartra, Sidnei, Pedraza; Carvalho, Guardado; Canales, Fekir, Tello; Loren.
Betting & Match Odds
Barcelona are 1/4 favourites to win this match with bet365. Betis are on offer at 10/1, while the draw is available at 21/4.
After a summer dominated by the transfer pursuits of forwards Antoine Griezmann and Neymar, Barcelona looked curiously blunt when they got the new Spanish season underway last Friday.
Though it took a moment of sublime quality from Aritz Aduriz to down them, Ernesto Valverde's side struggled to create chances.
With Messi still not ready to return and starting forwards Luis Suarez and Ousmane Dembele also injured, the expectation in this game will be on Antoine Griezmann to deliver, with fans eagerly anticipating his competitive home debut.
Valverde is looking forward to it too, but says Griezmann has to contribute more after a muted performance on his competitive debut.
"He has to be more involved in the play and always be looking to get involved," he said.
"It is good to have him near the area because of his movement but that will only work if we completely dominate games."
Gerard Pique is set to make his 500th appearance for the club, though he isn't likely to come up against Betis' new star forward Borja Iglesias, who is injured. Pique's fellow La Masia graduate Cristian Tello, though, is looking forward to his trip back to Catalonia.
"It's the team that gave me the opportunity to debut in the first division," Tello told Barca's website. "I have a lot of love for Barça and I appreciate all the people there.
"I experienced the best moments as a player who was trying to get to the top, and when you join the first team with all the enthusiasm that entails. I think it will be very special to return.
"We are aware that to win at Camp Nou we have to play a practically perfect match, but I think we have the team for it. Against Valladolid we had some bad luck, but we were very focused. I think we can win again at Camp Nou."