Patouillet joined Lyon in 2019 from Domtac. He was a central figure in Lyon's reserve team. The French youngster saved the decisive penalty in Lyon’s 2021-22 Coupe Gambardella final, helping Lyon win the shootout 5-4 after a 1-1 draw in regular time. Despite some incredible performances, Patouillet hasn't been able to break into the first team with competition from Dominik Greif and Remy Descamps.