14 goals have been shared in the last four meetings between these two sides, and weakened defences suggest another high-scoring affair on Wednesday.
Best bets for Monaco vs Tottenham
- Match drawn at odds of 3.50 with Betway
- Over 3.5 goals at odds of 2.50 with Betway
- Richarlison anytime goalscorer at odds of 2.75 with Betway
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Our analysis: Form of both teams
- Score prediction – Monaco 2-2 Tottenham
- Goalscorers prediction – Monaco: Fati, Balogun – Tottenham: Richarlison, Johnson
With four points to their name from their opening two UCL league phase games, Tottenham are aware a win in Monaco would put them halfway to securing a place in the top 16.
Their French opponents, AS Monaco, have just one point from their first two matches. Sebastien Pocognoli’s side shipped six goals in 180 minutes. However, their entertaining 2-2 draw with Manchester City in their previous league phase game was encouraging. That result was all the more positive given they had been beaten 4-1 by Club Brugge last month.
Thomas Frank will have to pick a weakened backline for the trip to the Principality on Wednesday night. Destiny Udogie and Cristian Romero are highly doubtful to be fit to travel, after the pair suffered fresh issues prior to the Aston Villa match.
Monaco have an equally lengthy injury list, but Folarin Balogun, Ansu Fati and Mika Biereth are impressive attacking options.
Probable lineups for Monaco vs Tottenham
AS Monaco expected lineup: Kohn, Diatta, Salisu, Henrique, Kehrer, Teze, Coulibaly, Ouattara, Akliouche, Fati, Balogun
Tottenham Hotspur expected lineup: Vicario, Spence, Porro, Danso, Van de Ven, Bentancur, Bergvall, Sarr, Johnson, Simons, Richarlison
Fresh injuries could lead Spurs to settle for a draw
Thomas Frank is set to take his side to the Stade Louis II without influential captain, Cristian Romero, while Destiny Udogie is also expected to miss out on Wednesday. Kevin Danso is the likely deputy, but Spurs won’t be at full strength by any means.
Monaco have plenty of absentees of their own. Former Tottenham stalwart, Eric Dier, won’t be fit to face his former employers after suffering a hamstring issue. New Monaco boss, Sebastien Pocognoli, is still waiting for Paul Pogba to get the green light to play and bolster his midfield.
With both squads stretched, but still offering plenty of attacking threat, we could see an entertaining stalemate on Wednesday night.
- Monaco vs Tottenham Bet 1: Match drawn at odds of 3.50 with Betway
Goals aplenty at both ends
In their previous four meetings in the Champions League, neither side has managed to keep a clean sheet. Notably, 14 goals have been shared in their last four matches. Monaco have also averaged three goals conceded from their first two games this campaign. This makes Over 3.5 Goals the value play from our trio of Monaco vs Tottenham predictions.
The betting markets believe there is only a 40% chance of this happening, but this probability seems low. Monaco need a win to ignite their league phase campaign, while Spurs generally adopt a fluid style of play.
In fact, PSG aside, Monaco are the joint second-highest scorers in Ligue 1 so far this season. The likes of Ansu Fati and Mika Biereth are serious threats for the home side. Meanwhile, Richarlison has a strike rate of 37.50% so far in the Premier League.
- Monaco vs Tottenham Bet 2: Over 3.5 goals at odds of 2.50 with Betway
Backing Richarlison to break his 25/26 UCL duck
Speaking of Richarlison, there is some value in backing him to score on Wednesday. The Brazilian appears set to lead the line with Mathys Tel ineligible.
Richarlison is often used by Thomas Frank as a false nine. Despite some indifferent displays in 2025/26 to date, his 37.50% strike rate is more than respectable.
The betting markets believe he has a 36.36% chance of scoring on Wednesday night. Given that Richarlison seems set to be Spurs’ focal point in attack, this is well worth backing.
- Monaco vs Tottenham Bet 3: Richarlison anytime goalscorer at odds of 2.75 with Betway