Tebogo Mashingo thrust AmaZulu ahead seven minutes into the match before Lebohang Nkaki's 56th-minute penalty levelled matters at King Goodwill Zwelithini Stadium on Friday.
After collecting a point, Usuthu remain sixth on the table with four points more than Kaizer Chiefs.
The result extended Polokwane's winless run to four games and they are placed seventh.