Barcelona travel to Real Betis on Wednesday night in a rescheduled La Liga game which could see Xavi Hernandez's men move eight points clear at the top of the table.
The Blaugrana are currently five points ahead of rivals Real Madrid who play on Thursday evening and victory for the Blaugrana at the Estadio Benito Villamarin would see them open up a healthy lead over Los Blancos.
Real Betis vs Barcelona latest odds
These two sides met in the semi-finals of the Spanish Super Cup two weeks ago with the game ending 2-2 and the Catalans triumphing on penalties.
Another draw can be backed at 14/5 (3.80) with bet365 while the hosts are offered at 4/1 (5.00) and the visitors at 4/6 (1.66).
Real Betis vs Barcelona first goal scorer odds
Robert Lewandowski returns from his three-match La Liga suspension and the Polish forward is the shortest priced player to break the deadlock in the city of Seville at 13/5 (3.60).
In the absence of the injured Ousmane Dembele, Ansu Fati could start and the young Spanish international is offered at 13/2 (9.50) with Betis' top scorer this term Borja Iglesias available at 8/1 (9.00).
Real Betis vs Barcelona preview
Betis have been tough to beat at home this season, suffering just one defeat in their eight league games and Los Verdiblancos are likely to make life tough for Barcelona.
Manuel Pellegrini's men have seen a drop off in form since the return from the World Cup break, but still boast some exceptional players and with their imposing stadium full of passionate supporters they remain a tough proposition for any side.
Barca have the best defensive record of any side in Europe's major leagues having conceded just six goals all season, yet there should be interest in backing the hosts to score as they have done in each of their last nine competitive fixtures against the Catalans.
Real Betis vs Barcelona tips and predictions
Both teams to score is offered at 4/5 (1.80) and looks an obvious selection, one which has paid out in eight of the last nine meetings.
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Odds correct at the time of writing. Please gamble responsibly.