The pair have been important figures for the League Two team but have already had spells out of the team this season.
The Red Dragons will have to do without the two players for almost two months, the coach has confirmed.
WHAT THEY SAID
"To come through and finish October with a win is great for us," he said. "We need to patch a few people up. Eoghan O’Connell looks to be out for eight weeks, Barny (Ryan Barnett) looks to be out for eight weeks.”
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WHAT HAPPENS NEXT?
Wrexham's next match is against Mansfield Town in the FA Cup on November 4.