Comment and Analysis
Jose Mourinho will be without the duo as well as Phil Jones and Matteo Darmian, while Ander Herrera is suspended for Wednesday's game
The MLS Cup champions have seen some big changes in the offseason, but look ready to defend the title in 2017.
Bolstered by a strong nucleus of young talent and some impressive veterans, the Union will be looking to ride a revamped roster to a deep playoff run.
After another disappointing playoff exit, the Red Bulls made a major change this winter — and will be hoping to change their postseason fortunes.