(C)Getty Images- Juara bertahan: Manchester City
- Tim promosi: Cardiff City, Fulham, Wolverhampton Wanderers
- Kick-off: Jumat, 10 Agustus 2018 pukul 20:00 CET atau Sabtu, 11 Agustus 2018 pukul 02:00 WIB
- Laga pembuka: Manchester United vs Leicester City
- Selesai: Minggu, 12 Mei 2019
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| ARSENAL | BOURNEMOUTH |
| Berita & Skuat Jadwal & Hasil Pertandingan Stadion: Emirates Stadium Julukan: The Gunners Pelatih: Unai Emery | Berita & Skuat Jadwal & Hasil Pertandingan Stadion: Vitality Stadium Julukan: The Cherries, Boscombe Pelatih: Eddie Howe |
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| BRIGHTON & HOVE ALBION | BURNLEY |
| Berita & Skuat Jadwal & Hasil Pertandingan Stadion: Amex Stadium Julukan: The Seagulls, Albion Pelatih: Chris Hughton | Berita & Skuat Jadwal & Hasil Pertandingan Stadion: Turf Moor Julukan: The Clarets Pelatih: Sean Dyche |
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| CARDIFF CITY | CHELSEA |
| Berita & Skuat Jadwal & Hasil Pertandingan Stadion: Cardiff City Stadium Julukan: The Bluebirds Pelatih: Neil Warnock | Berita & Skuat Jadwal & Hasil Pertandingan Stadion: Stamford Bridge Julukan: The Blues, The Pensioners Pelatih: Maurizio Sarri |
| CRYSTAL PALACE | EVERTON |
| Berita & Skuat Jadwal & Hasil Pertandingan Stadion: Selhurst Park Julukan: The Eagles, The Glaziers Pelatih: Roy Hodgson | Berita & Skuat Jadwal & Hasil Pertandingan Stadion: Goodison Park Julukan: The Toffees, The Blues Pelatih: Marco Silva |
| FULHAM | HUDDERSFIELD TOWN |
| Berita & Skuat Jadwal & Hasil Pertandingan Stadion: Craven Cottage Julukan: The Cottagers, The Whites, The Lily Whites Pelatih: Slavisa Jokanovic | Berita & Skuat Jadwal & Hasil Pertandingan Stadion: John Smith's Stadium Julukan: The Terriers Pelatih: David Wagner |
| LEICESTER CITY | LIVERPOOL |
| Berita & Skuat Jadwal & Hasil Pertandingan Stadion: King Power Stadium Julukan: The Foxes Pelatih: Claude Puel | Berita & Skuat Jadwal & Hasil Pertandingan Stadion: Anfield Julukan: The Reds Pelatih: Jurgen Klopp |
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| MANCHESTER CITY | MANCHESTER UNITED |
| Berita & Skuat Jadwal & Hasil Pertandingan Stadion: Etihad Stadium Julukan: Citizens, Sky Blues, City Pelatih: Pep Guardiola | Berita & Skuat Jadwal & Hasil Pertandingan Stadion: Old Trafford Julukan: The Red Devils Pelatih: Jose Mourinho |
| NEWCASTLE UNITED | SOUTHAMPTON |
| Berita & Skuat Jadwal & Hasil Pertandingan Stadion: St James' Park Julukan: The Magpies Pelatih: Rafael Benitez | Berita & Skuat Jadwal & Hasil Pertandingan Stadion: St Mary's Stadium Julukan: The Saints Pelatih: Mark Hughes |
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| TOTTENHAM HOTSPUR | WATFORD |
| Berita & Skuat Jadwal & Hasil Pertandingan Stadion: Wembley Julukan: Spurs, The Lilywhites Pelatih: Mauricio Pochettino | Berita & Skuat Jadwal & Hasil Pertandingan Stadion: Vicarage Road Julukan: The Hornets, The Golden Boys, Yellow Army, The 'Orns Pelatih: Javi Gracia |
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| WEST HAM UNITED | WOLVERHAMPTON WANDERERS |
| Berita & Skuat Jadwal & Hasil Pertandingan Stadion: London Stadium Julukan: The Irons, The Hammers, The Academy of Football Pelatih: Manuel Pellegrini | Berita & Skuat Jadwal & Hasil Pertandingan Stadion: Molineux Julukan: Wolves, The Wanderers Pelatih: Nuno Espirito Santo |