The game was moved from Poltava to Kiev by UEFA due to ongoing security concerns, but Vorskla have expressed annoyance at the decision and suggested that the game may not actually go ahead.
With qualification secured, Unai Emery has brought an experimental squad to Ukraine, opting to rest some star players ahead of the weekend's North London Derby against Tottenham.
Vorskla, meanwhile, are still in with a chance of progressing from Group E, but they will need to achieve a favourable result against the Gunners.
|Game||Vorskla vs Arsenal|
|Date||Thursday, November 29|
|Time||5:55pm GMT / 12:55pm ET|
TV Channel, Live Stream & How To Watch
In the United States (US), the game can be watched live on TV on Galavision and streamed live online via B/R Live.
|US TV channel||Online stream|
In the United Kingdom (UK), the game can be watched live on TV on BT Sport 2 and it can be streamed live online using the BT Sport app.
|UK TV channel||Online stream|
|BT Sport 2||BT Sport app|
Squads & Team News
|Goalkeepers||Shust, Tkachenko, Riznyk|
|Defenders||Giorgadze, Perduta, Yakubu, Sapai, Martynenko, Chyzhov, Dallku, Kane, Artur|
|Midfielders||Skliar, Kadymian, Habelok, Sharpar, Mysyk, Chesnakov, Odariuk, Kravchenko, Kobakhidze, Sakiv, Chertkoiev, Rebenok|
|Forwards||Serhiichuk, Kulach, Careca, Kolomoets|
Vorskla have not indicated any fresh injury concerns and so should have a full panel to choose from for their game against the Gunners.
Potential Vorskla XI: Shust; Perduta, Dallku, Chesnakov, Artur; Sapai, Skliar, Sharpar, Rebenok; Kulach; Kolomoets.
|Goalkeepers||Cech, Iliev, Martinez|
|Defenders||Lichtsteiner, Holding, Jenkinson, Medley, Osei-Tutu, Thompson|
|Midfielders||Elneny, Mkhitaryan, Ramsey, Maitland-Niles, Guendouzi, Gilmour, Smith Rowe|
|Forwards||Nketiah, Willock, John-Jules, Saka|
Emery has announced a 20-man travelling squad for the match and the likes of Pierre-Emerick Aubameyang, Mesut Ozil and Shkodran Mustafi have all been left out.
The Spanish coach has packed his panel with a plethora of academy graduates, with the likes of Petr Cech, Aaron Ramsey, Stephan Lichtsteiner and Henrikh Mkhitaryan providing some experience.
Arsenal XI: Cech; Lichtstetiner, Jenkinson, Holding, Maitland-Niles; Guendouzi, Elneny; Willock, Ramsey, Smith Rowe; Nketiah.
Betting & Match Odds
Arsenal are 3/4 favourites to win the game in Ukraine according to bet365. Vorskla's chances of winning are rated 17/4 and a draw is available at 11/4.
Arsenal made light work of Vorskla when the sides met at the Emirates Stadium back in September, with Aubameyang, Ozil and Danny Welbeck combining to ensure a 4-2 victory.
However, it is likely to be a much closer affair on Thursday, considering Emery's decision to rest his star players ahead of the North London Derby against Spurs.
“We have a big responsibility with young players,” the Gunners boss told reporters. “At Arsenal, every year we are working very well with young players.
“When there are matches like Thursday’s in a very big week for us, where we are playing a lot of matches, we have players to cover here. We need to give them chances."
Indeed, though a cloud hangs over the game, it represents a golden opportunity for emerging talent such as Emile Smith Rowe and Eddie Nketiah to convince the Spaniard of their long-term worth to his team.