It was an encounter that saw three goals being scored in the opening 10 minutes.
Peter Shalulile was the first on the scoresheet by easily connecting an Iqraam Rayners cool assist in the first minutes.
In the seventh minute, Rayners then shrugged off his marker to fire home after being fed by Marcelo Allende as Sundowns threatened to go on a rampage.
But TS Galaxy pulled a goal back three minutes later when Sphiwe Mahlangu rounded Masandawana goalkeeper Jody February and finished into an empty net after being set up by Victor Letsoalo.
Then after 26 minutes, the Rockets went a man down when Letsoalo received a straight red card for a dangerous challenge on Bathusi Aubaas.
The Tshwane giants restored a two-goal lead seven minutes before halftime when Jayden Adams struck from inside the box.
Rayners returned to grab Masandawana's fourth and seal his double with a goal three minutes into the second half, making the 4-1 lead difficult for the visitors to come back.
After second-placed Pirates had cut Sundowns' lead to nine points earlier in the day, the Brazilians then went back to 12 points clear at the top.
Saturday's result was revenge by Masandawana who were beaten 1-0 by TS Galaxy last week.