Recalled to the squad for the first time in over three years, Jermain Defoe is priced at 9/1 (10.00) with bet365 to mark his return to the fold by opening the scoring at the Westfalenstadion, and 3/1 (4.00) to merely score the 20th goal of his international career.
Having only recently rediscovered the form that helped fire Leicester City to a shock Premier League title last season, Jamie Vardy can also be backed at 3/1 (4.00) to build on his five goals in the last six club appearances by punishing a defence he opened his international account against one year ago.
Also struggling to recreate last season’s impressive form, Marcus Rashford is another 3/1 (4.00) shot to boost his own Three Lions credentials with a second senior international goal.
However, considering his prolific recent form for Tottenham, Dele Alli may be the best bet of all at 4/1 (5.00) to get on the scoresheet once again after striking in each of his last four club appearances.
At the other end of the pitch, Joachim Low is comparatively spoilt for choice with a forward line rich in goal-scoring talent.
While he may be failing to reach his own high standards in front of goal for Bayern Munich this season, Thomas Muller’s record of 36 in 83 for Die Mannschaft makes him a 9/2 (5.50) favourite to break the deadlock and 11/8 (2.38) to strike anytime.
Similarly, Mario Gomez’s own impressive tally of 29 goals in 69 internationals means he is a joint 11/8 (2.38) front runner to hit the net for his nation, having done so in each of his last three games for Wolfsburg.
In fine form for Bundesliga surprise package RB Leipzig, youngster Timo Werner can be backed at 7/4 (2.75) to mark his full international debut with a goal, while at the other end of the spectrum Lukas Podolski is priced at 2/1 (3.00) to sign off by finding the net in his final match before retiring.