After allowing Romelu Lukaku to leave without a high-profile replacement, Ole Gunnar Solskjaer will be looking for his other forwards to step up in front of goal when Chelsea visit Old Trafford on Sunday.
The Belgium international was the Red Devils' top-scoring striker last season but has left for Inter after being deemed ill-suited to the manager's preferred tactics.
Two goals adrift of Lukaku with 10 league goals, Marcus Rashford is 888Sport's 19/4 (5.75) favourite to help banish his memory by breaking the deadlock at Old Trafford, or 37/20 (2.35) to strike anytime.
However, the England striker has been playing a wider role in pre-season, with Anthony Martial enjoying a central role.
Having scored twice in last season’s 2-2 draw at Stamford Bridge, he looks a tempting bet at 43/20 (3.15) to stake his claim for the striker spot with another big goal in this clash.
Alternatively, Juan Mata offers an even more lucrative potential long shot to come back to haunt his former club for the second meeting in a row, priced at a generous 4/1 (5.00).
Meanwhile, the Blues will also have to cope without a departed Belgian star, although Eden Hazard’s departure to Real Madrid is likely to leave a far bigger hole.
GettySeemingly brought in as his long-term successor, Christian Pulisic can be backed at a lengthy 10/1 (11.00) to begin to live up to that task with the opener here, or 17/4 (5.25) to score anytime.
Frank Lampard is likely to choose either Olivier Giroud or Tammy Abraham to lead the line, with his faith in youth perhaps making the latter more likely.
Prolific in the Championship on loan at Aston Villa last season, the 21-year-old is available at 41/20 (3.05) to make the step up with a first top flight goal for Chelsea.
Having scored just two goals in 27 league appearances under Maurizio Sarri, Giroud is priced at 5/2 (3.50) to get off to a more promising start by hitting the back of the net against United.
Martial to score anytime at 43/20 (3.15) for a 1pt stake with 888Sport
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