The match pits two of the league's form teams against each other, but it is Bayern who enter with an aura of invincibility. Kompany's side sits atop the table with a perfect record of 24 points from eight games, having scored 30 goals and conceded just four.
They are currently on a 14-game winning streak in all competitions, a European record they will be looking to extend. Bayern's last defeat in any competition came in the Club World Cup quarter-final against Paris Saint-Germain. Their last Bundesliga loss was in March against Bochum (2-3).
Despite Leverkusen's own strong run of five wins and a draw in their last six league games, they are already seven points adrift of the runaway leaders.
Boosting Bayern's chances of nullifying Grimaldo's dead-ball threat is the timely return of captain Manuel Neuer. The 39-year-old goalkeeper is set to return to the starting lineup after a two-match absence.
Neuer missed the 4-1 DFB-Pokal victory over Cologne due to suspension and was rested for the subsequent 3-0 league win against Borussia Monchengladbach.
In his absence, 22-year-old Jonas Urbig deputised and gained valuable match practice. However, Neuer's experience and renowned shot-stopping ability will be a welcome addition as Bayern prepare to face Grimaldo's pinpoint free-kicks.