The Carolina Panthers kick off their 2025 campaign on Sunday afternoon with a road trip to EverBank Stadium to face the Jacksonville Jaguars.
Carolina enters the year with a secondary that looks serviceable, anchored by a cornerback duo expected to benefit from an upgraded pass rush. Neither group stands among the league’s elite, but together they could form a more cohesive unit, and Jacksonville will be the first real test.
For the Jaguars, the approach may lean heavily on Trevor Lawrence and the passing game. With Carolina bolstering its defensive front throughout the offseason, new head coach Liam Coen could experience some early growing pains as he tries to get the offense firing on all cylinders.
| Date | Sunday, September 7, 2025 |
| Time | 1:00 pm ET / 2:00 pm CT/ 10:00 am PT |
| Venue | EverBank Stadium (Jacksonville, Florida) |
| TV Channel | FOX |
| Streaming | Fubo |
| Buy Tickets | Stubhub |
| Odds | -158 (Jaguars) | +134 (Panthers) |
Jacksonville Jaguars vs Carolina Panthers roster & injury news
Jacksonville Jaguars team news
The Jaguars head into Week 1 dealing with a handful of injury concerns that could impact both sides of the ball. Linebacker Jalen McLeod and corner Caleb Ransaw are both sidelined on injured reserve, along with wide receiver Joshua Cephus. In the trenches, veteran defensive tackle Arik Armstead is questionable, while the secondary could be shorthanded if corner Tyson Campbell isn’t cleared to go.
| Position | Players |
|---|---|
| Offense | Trevor Lawrence, Nick Mullens (QB); LeQuint Allen Jr., Tank Bigsby, Travis Etienne Jr., Bhayshul Tuten (RB); Dyami Brown, Travis Hunter, Tim Patrick, Brian Thomas Jr., Parker Washington (WR); Hunter Long, Johnny Mundt, Brenton Strange (TE); Robert Hainsey, Jonah Monheim (C); Ezra Cleveland, Chuma Edoga, Patrick Mekari, Wyatt Milum (G); Anton Harrison, Walker Little, Cole Van Lanen (OT) |
| Defense | BJ Green II, Josh Hines-Allen, Emmanuel Ogbah, Dawuane Smoot, Danny Striggow, Travon Walker (DE); Arik Armstead, DaVon Hamilton, Austin Johnson, Khalen Saunders, Maason Smith (DT); Yasir Abdullah, Dennis Gardeck, Jack Kiser, Devin Lloyd, Ventrell Miller, Foyesade Oluokun (LB); Christian Braswell, Montaric Brown, Tyson Campbell, Jarrian Jones, Jourdan Lewis (CB); Antonio Johnson, Rayuan Lane III, Eric Murray, Darnell Savage, Andrew Wingard (S) |
| Special Teams | Cam Little (PK), Logan Cooke (P), Ross Matiscik (LS) |
Carolina Panthers team news
The Panthers aren’t without their own setbacks either. Wideout Jalen Coker has been placed on injured reserve, while the offensive line faces uncertainty with Ikem Ekwonu and Damien Lewis both listed as questionable. Depth has also taken a hit with guard Ja’Tyre Carter landing on IR, and on defense, linebacker Nic Scourton is battling a knock that leaves his status up in the air.
| Position | Players |
|---|---|
| Offense | Andy Dalton, Bryce Young (QB); Rico Dowdle, Trevor Etienne, Chuba Hubbard (RB); Dalevon Campbell, Jimmy Horn Jr., Xavier Legette, Tetairoa McMillan, David Moore, Hunter Renfrow, Brycen Tremayne (WR); Mitchell Evans, James Mitchell, Ja'Tavion Sanders, Tommy Tremble (TE); Austin Corbett, Cade Mays (C); Brady Christensen, Robert Hunt, Damien Lewis, Chandler Zavala (G); Ikem Ekwonu, Taylor Moton, Yosh Nijman (OT) |
| Defense | Derrick Brown, A'Shawn Robinson (DE); Bobby Brown III, Cam Jackson, Tershawn Wharton (DT); Claudin Cherelus, Thomas Incoom, DJ Johnson, Patrick Jones II, Bam Martin-Scott, Christian Rozeboom, Nic Scourton, Princely Umanmielen, Trevin Wallace, D.J. Wonnum (LB); Akayleb Evans, Jaycee Horn, Mike Jackson, Damarri Mathis, Chau Smith-Wade, Corey Thornton (CB); Tre'von Moehrig, Lathan Ransom, Demani Richardson, Nick Scott (S) |
| Special Teams | Ryan Fitzgerald (PK), Sam Martin (P), JJ Jansen (LS) |
Jaguars vs Panthers head-to-head record
The history between the Panthers and Jaguars is as balanced as it gets. The two franchises have squared off eight times, with each side claiming four victories to keep the all-time series dead even.
Which channel is Jaguars vs Panthers game on?
The Jacksonville Jaguars vs Carolina Panthers game in Week 1 of the 2025 NFL season will air live on FOX in the US. Fans will be able to catch the coverage onFubo (Try for free today!).
More details on where to watch the game in the United States, including streaming options, will be released soon, so keep an eye out for our dedicated coverage.
For fans outside the U.S. looking to stay plugged into the action,NFL Game Pass on DAZN is the ultimate ticket. It serves up more than 200 regular-season and playoff matchups, complete Super Bowl coverage, plus access to NFL Network, NFL RedZone, and plenty more to keep you locked in all year long.
How to buy Jaguars vs Panthers ticket
Tickets are already up for grabs on StubHub, with entry starting at $386. From there, prices climb through the tiers — $300, $400, $500, $600, $700, $800, $900, $1,000, and stretching all the way into the premium ranges of $2,000, $3,000, $4,000, $5,000, $6,000, and topping out at $10,406 for the best seats in the house.
Check the link below for the full breakdown of how to purchase tickets to NFL games.
READ MORE: NFL 2025 Tickets: Prices, deals, season tickets & membership information
Jaguars vs Panthers Fantasy Football
Fantasy managers should keep their eyes firmly on the explosive playmakers from both sides, with rookie wideouts looking primed to steal the spotlight. For Carolina, Bryce Young is tipped for a breakout showing, projected to clear 280 passing yards with multiple scores. His growing poise and command of a revamped offense make him a strong QB1 play. Rookie receiver Tetairoa McMillan profiles as his top vertical weapon, expected to draw heavy targets in what could be a high-scoring affair.
Over in Jacksonville, Travis Hunter carries big-play potential, with a long touchdown well within reach, while Brian Thomas Jr. has the upside to top 100 yards against the Panthers’ secondary. On the ground, Carolina’s Chuba Hubbard shapes up as a useful flex piece given the matchup, while Jacksonville’s backfield is murkier but still worth monitoring for hidden value.
Fantasy takeaways in short:
Roll with Bryce Young (15.9 projected fpts for Week 1) and Tetairoa McMillan (15.9 projected fpts for Week 1) as reliable Panthers plays.
Lock in Travis Hunter and Brian Thomas Jr. as Jaguars’ top fantasy weapons.
Slot Chuba Hubbard in as a flex with upside.
Keep tabs on Jaguars RB usage before committing.
Jaguars vs Panthers Game Predictions
Last year, the Carolina Panthers and Jacksonville Jaguars were anchored to the bottom of the league defensively, finishing 31st and 32nd in both opponent yards per play and opponent EPA per play. Neither franchise made the kind of offseason moves that suggest those defensive woes will suddenly vanish.
That said, the offenses paint a far brighter picture. Bryce Young closed out 2024 playing the best football of his young career, showing real signs of growth and confidence. On the other side, a fully fit Trevor Lawrence combined with new head coach Liam Coen gives Jacksonville’s attack plenty of upside heading into 2025. With both teams boasting weapons capable of putting up points in a hurry, this matchup feels destined to turn into a shootout.
The numbers lean toward Jacksonville. The Jaguars enter with a 58.9% chance of toppling the Panthers, while Carolina sits at 40.8%, leaving only a slim margin for the unlikely outcome of a tie.
Jaguars vs Panthers Odds
Spread: Jaguars -3.5 (-105), Panthers +3.5 (-115)
Total: 46.5 (Over -105/Under -115)
Moneyline: -158 (Jaguars) | +134 (Panthers)
More NFL news and coverage
- Jaguars 2025 NFL schedule: TV channel, livestream & where to watch the games
- Panthers 2025 NFL schedule: TV channel, livestream & where to watch the games
- How to watch and live stream NFL football for free and without cable
- 2025 fantasy football rankings: Running back (RB) | Wide receiver (WR) | Tight end (TE) | Quarterback (QB)