Sevilla travel to Slavia Prague on Thursday evening with the La Liga side hoping to avoid a shock exit from the Europa League in the last 16 at the Sinobo Stadium.
Pablo Machin's men were held to a 2-2 draw by the leaders of the Czech league when they met at the Estadio Sanchez Pizjuan last week, meaning they have work to do when they visit Prague.
Latest odds
Sevilla's away form in La Liga has been extremely poor, with the Andalusians remaining winless on the road since September.
In the Europa League this term, Machin's men lost two of their three away games in their group - although they did record a win at Lazio in the previous round. The visitors are offered at 21/20 (2.05) to win with bet365.
Slavia, for their part, are unbeaten at home in Europe this season having drawn two and won two in front of their own fans. The hosts can be backed at 11/4 (3.75) to win with the draw available at the same price.
Team news
Sevilla are without Nolito, Ibrahim Amadou, Joris Gnagnon, Aleix Vidal and Sergio Escudero. Goalkeeper Tomas Vaclik had to come off in the first leg and missed the weekend game in La Liga, but should be available on his return to his home country.
Preview
Slavia Prague were incredibly fortunate to score twice in the south of Spain last week. Indeed, their first goal was a deflected shot and their second a bizarre ricochet which scorer Alex Gral knew nothing about.
Even then, Sevilla created enough chances to win the game and a side with their amount of European know-how must surely be backed to overcome their inferior and inexperienced opponents.
Slavia are one of the weakest teams left in the competition and backing the five-time winners of the Europa League to triumph in Prague makes plenty of sense.
Tips and predictions
The price for the visitors to win in ninety minutes is big enough to tempt. Sevilla are also offered at 21/10 (3.10) to be ahead at half time and full time, as they were away to Lazio in the previous round, and that could be a solid value option.
Odds correct at the time of writing. Please gamble responsibly.
Sevilla to win at 21/20 (2.05) for a 3pt stake with bet365