Jorginho and his agent are poised to finalise the move after a payment structure between City and Napoli was agreed earlier this week.
City are still in talks with Leicester regarding a move for Riyad Mahrez, although there is a difference in opinion regarding the winger’s value.
The Premier League champions had found themselves in that position with Napoli for the best part of the last two months, although there had always been a confidence and a willingness from both sides to get a deal done.
After weeks of further haggling a fee of around £46m ($60.4m) plus bonuses worth around £6m ($7.9m) was provisionally agreed on Monday.
Napoli president Aurelio De Laurentiis has now given his sporting director, Cristiano Giuntoli, the go-ahead to rubber-stamp the agreement.
The Blues had been hoping to bring him to the club ahead of the World Cup, but adjusted their expectations after Napoli rejected their initial proposal.
Jorginho recently spent some time with family in Brazil, his homeland, after learning that the deal had dragged on, but returned to Europe this week and is now ready to sign a five-year deal at the Etihad Stadium.
City still indeed to sign Mahrez this summer but have been frustrated by Leicester’s demands.
Unlike in their pursuit of Jorginho, City would have an alternative option if their pursuit of Mahrez comes to nothing - Bayer Leverkusen’s Leon Bailey has been watched closely - but negotiations with Leicester will continue in the coming weeks.