Brendan Rodgers' side missed out on a place in the group stage of the Champions League so they will be eager to redeem themselves by mounting a strong push for glory in UEFA's second-tier club tournament.
For the visitors, the game offers an ideal opportunity to exact revenge, but they will be keen not to let such thoughts get in the way of their strategy.
|Game||Celtic vs Rosenborg|
|Date||Thursday, September 20|
|Time||8pm BST / 3pm ET|
TV Channel, Live Stream & How To Watch
In the United States (US) the game will not be available to watch live on television but it can be streamed live online using B/R Live.
|US TV channel||Online stream|
The game can be watched live on television in the United Kingdom (UK) via BT Sport 3 and it can be streamed live online using the BT Sport app.
|UK TV channel||Online stream|
|BT Sport 3||BT Sport app|
Squads & Team News
|Goalkeepers||Gordon, Bain, Hazard|
|Defenders||Hendry, Simunovic, Gamboa, Boyata, Benkovic, Lustig, Ajer, Ralston, Tierney, Izaguirre|
|Midfielders||Brown, Sinclair, Hayes, Morgan, Christie, Rogic, Ntcham, Mulumbu, McGregor, Forrest, Eboue, Arzani|
|Forwards||Griffiths, Edouard, Johnston|
Celtic have concerns over the fitness of Kristoffer Ajer, who is stricken with a virus, while Josip Simunovic remains sidelined. That means there may be some shuffling at the back, with Mikael Lustig or Jack Hendry capable of filling in.
Confirmed Celtic XI: Gordon; Lustig, Boyata, Benkovic, Tierney; Brown, Ntcham; Rogic, Forrest, McGregor; Edouard
|Goalkeepers||Hansen, Ostbo, Sandberg|
|Defenders||Hedenstad, Meling, Reginiussen, Hovland, Gersbach, Reitan, Serbecic, Ogbu, Heggem, Williams|
|Midfielders||Denic, Jensen, Konradsen, Trondsen, Lundemo, Skarsem, Johnsen, Bjornebye|
|Forwards||Bendtner, Vilhjalmsson, De Lanlay, Soderlund, Levi, Helland, Jebali, Adegbenro, Haltvik, Botheim, Brattbakk|
Nicklas Bendtner, who was recently in the headlines for an altercation involving a taxi driver, looks set to miss the game with a thigh injury. Samuel Adegbenro is another expected absentee.
Confirmed Rosenborg XI: Hansen, Hedenstad, Hovland, Reginiussen, Meling, Denic, Jensen, Konradsen, De Lanlay, Jebali, Soderlund.
Betting & Match Odds
At 1/2 (per bet365) Celtic are firm favourites to come out on top in the game. Rosenborg are priced at 13/2 to win at Parkhead and a draw is available at 7/2.
The wonderful mechanics of chance have conspired to pair Celtic and Rosenborg for the third time in European competition in the space of two seasons.
Celtic have come out on top on both occasions, narrowly winning 1-0 on aggregate last season before improving to triumph 3-1 earlier this season in the Champions League qualification phase. The Bhoys subsequently failed overcome AEK Athens in the following round and thus missed out on a place in the Champions League group stage.
Having already beaten the Norwegians over four ties in recent memory, the Scottish champions undoubtedly boast a psychological edge, but they cannot afford to take anything for granted on Thursday.
"The dynamics are slightly different in terms of playing Rosenborg," Rodgers said.
"Previously, it has been knockout and maybe the first legs have been a little bit cagey, but the difficulty of the game is still there.
"Their system's very clear, it's very defined. They've got good balance in their team, clear identity, very structured, but also they've got very good individual players."
A win at home will set Celtic nicely on their way towards progression from Group B, with arguably tougher matches against RB Leipzig and Red Bull Salzburg to come in October.