Real Madrid will head to Vigo for their game in hand just behind Barca on head-to-head but knowing a win over the Europa League semi-finalists will all-but wrap up the championship with a round remaining.
For the past month, Celta coach Eduardo Berizzo has effectively turned his back on Spain's top tier to focus on the Europa League, with his team winning just one of their past eight La Liga fixtures and losing the other seven.
Without the threat of relegation, Celta have little to play for but if they can rise to the occasion against Madrid, it could open the door for Barca to retain the title.
|BEST BET||VALUE BET|
|Real Madrid to win La Liga at $1.16|
Celta have shown this season, however, that they can match Madrid as they defeated Los Blancos 4-3 on aggregate in the Copa del Rey quarter-finals.
You can have a double chance with Celta winning or claiming a draw at $4.50 .
Assuming Madrid do slip-up at the Estadio de Balaidos, the Spanish title will come down to Madrid's trip to Malaga and Barcelona's clash with Eibar at Camp Nou on Sunday.
Barca are rated $5.00 to win La Liga.
*Prices subject to change