The FA Cup clash against United has been regarded by Newport boss Graham Coughlan as the biggest in the club's history.
"It’ll be a hell of an occasion," he said. "It’s a fourth-round tie against Manchester United, for me the biggest club in this country, in Europe and the world. I know some people would lean towards the fifth-round game against Manchester City (in February 2019), but I’d say Manchester United all day long."