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Tottenham Hotspur have been hit with a significant injury concern as defender Jan Paul van Hecke has been forced to withdraw from the Netherlands national team squad. The summer signing sustained a foot problem during international duty, leaving manager Roberto De Zerbi facing a potential selection headache ahead of a crucial trip to Old Trafford.

Liverpool have been handed a significant injury concern after Cody Gakpo was forced to withdraw from the Netherlands squad during the current international break. The versatile forward sustained a knock during the early stages of the Oranje's recent UEFA Nations League clash, prompting his immediate return to Merseyside for further assessment.