Jacksonville Jaguars vs Kansas City Chiefs NFL Preview: Team news, betting, tickets, live stream, Fantasy Football and more

The spotlight shifts to Jacksonville on Monday night, where the Jaguars welcome the reigning powerhouse Kansas City Chiefs in a clash that feels bigger than just Week 5. 

At 3-1, Jacksonville sits atop the AFC South, brimming with belief and momentum. Kansas City, on the other hand, is wobbling at 2-2, still trying to rediscover the rhythm that made them the NFL's gold standard.

Four weeks in, these teams seem to be trending in opposite directions. Jacksonville's defense has been mean and stingy, while the ground game has finally found its bite. Trevor Lawrence doesn't have to be a superhero when his supporting cast is grinding out yards and keeping opponents frustrated. Kansas City did flash signs of their old brilliance last week against Baltimore, but cracks remain, on both sides of the ball.

Still, let's not kid ourselves: the Chiefs remain one of the NFL's crown jewels, a team built on pedigree and star power. That's why this game is so intriguing. The Jaguars aren’t just chasing a win, they're chasing validation, the kind of statement that echoes across the league.

But to make that noise, Jacksonville must rise to the occasion. Taking down Patrick Mahomes under the primetime lights isn't just another win—it's a declaration that the Jaguars are no longer the plucky upstarts, but a legitimate contender in the AFC arms race.

Jacksonville Jaguars vs Kansas City Chiefs kick-off time

6 Oct 2025 - 20:15

GEHA Field at Arrowhead Stadium

The Jaguars and Chiefs will meet in Week 5 of the NFL season at EverBank Stadium in Jacksonville, Florida, on Monday, October 6, 2025, starting at 8:15 pm ET.

Team news & squads

Jacksonville Jaguars vs Kansas City Chiefs lineups

Jacksonville Jaguars

JAX

Formation

Kansas City Chiefs

KC

Josh Allen

LeQuint Allen

Arik Armstead

Christian Braswell

Dyami Brown

Montaric Brown

Tyson Campbell

Ezra Cleveland

Logan Cooke

Chuma Edoga

Travis Etienne

Dennis Gardeck

BJ Green

Robert Hainsey

Davon Hamilton

Anton Harrison

Travis Hunter

Antonio Johnson

Austin Johnson

Jarrian Jones

Jack Kiser

Rayuan Lane

Trevor Lawrence

Jourdan Lewis

Walker Little

Cam Little

Devin Lloyd

Hunter Long

Ross Matiscik

Patrick Mekari

Ventrell Miller

Jonah Monheim

Quintin Morris

Johnny Mundt

Eric Murray

Emmanuel Ogbah

Foyesade Oluokun

Tim Patrick

Maason Smith

Dawuane Smoot

Brenton Strange

Brian Thomas Jr.

Bhayshul Tuten

Cole Van Lanen

Parker Washington

Andrew Wingard

Matt Araiza

Jeffrey Bassa

Nick Bolton

Marquise Brown

Jason Brownlee

Harrison Butker

Mike Caliendo

Leo Chenal

Jack Cochrane

Chamarri Conner

Bryan Cook

Mike Danna

Ashton Gillotte

Noah Gray

Jaden Hicks

Creed Humphrey

Kareem Hunt

Chris Jones

George Karlaftis

Travis Kelce

Patrick Mahomes

Cooper McDonald

Trent McDuffie

Jaylon Moore

Wanya Morris

Derrick Nnadi

Charles Omenihu

Isaih Pacheco

Nikko Remigio

Christian Roland-Wallace

Jalen Royals

Josh Simmons

Trey Smith

Brashard Smith

JuJu Smith-Schuster

Kingsley Suamataia

Jawaan Taylor

Tyquan Thornton

Jerry Tillery

Robert Tonyan

Drue Tranquill

Marlon Tuipulotu

Jaylen Watson

Joshua Williams

Nohl Williams

James Winchester

Xavier Worthy

Kansas City Chiefs

KC

JAX

-Line up

• 41

  Josh Allen

• 36

  LeQuint Allen

• 91

  Arik Armstead

• 21

  Christian Braswell

• 5

  Dyami Brown

• 30

  Montaric Brown

• 3

  Tyson Campbell

• 76

  Ezra Cleveland

• 9

  Logan Cooke

• 55

  Chuma Edoga

• 1

  Travis Etienne

• 47

  Dennis Gardeck

• 95

  BJ Green

• 73

  Robert Hainsey

• 52

  Davon Hamilton

• 77

  Anton Harrison

• 12

  Travis Hunter

• 26

  Antonio Johnson

• 99

  Austin Johnson

• 22

  Jarrian Jones

• 54

  Jack Kiser

• 25

  Rayuan Lane

• 16

  Trevor Lawrence

• 2

  Jourdan Lewis

• 72

  Walker Little

• 39

  Cam Little

• —

  Devin Lloyd

• 84

  Hunter Long

• 46

  Ross Matiscik

• 65

  Patrick Mekari

• 51

  Ventrell Miller

• 60

  Jonah Monheim

• 80

  Quintin Morris

• 86

  Johnny Mundt

• 29

  Eric Murray

• 90

  Emmanuel Ogbah

• 23

  Foyesade Oluokun

• 17

  Tim Patrick

• 94

  Maason Smith

• 98

  Dawuane Smoot

• 85

  Brenton Strange

• 7

  Brian Thomas Jr.

• 33

  Bhayshul Tuten

• 70

  Cole Van Lanen

• 11

  Parker Washington

• 42

  Andrew Wingard

Substitutes

KC

-Line up

• 14

  Matt Araiza

• 31

  Jeffrey Bassa

• 32

  Nick Bolton

• 5

  Marquise Brown

• 89

  Jason Brownlee

• 7

  Harrison Butker

• 66

  Mike Caliendo

• 54

  Leo Chenal

• 43

  Jack Cochrane

• 27

  Chamarri Conner

• 6

  Bryan Cook

• 51

  Mike Danna

• 97

  Ashton Gillotte

• 83

  Noah Gray

• 21

  Jaden Hicks

• 52

  Creed Humphrey

• 29

  Kareem Hunt

• 95

  Chris Jones

• 56

  George Karlaftis

• 87

  Travis Kelce

• 15

  Patrick Mahomes

• 59

  Cooper McDonald

• 22

  Trent McDuffie

• 77

  Jaylon Moore

• 64

  Wanya Morris

• 92

  Derrick Nnadi

• 90

  Charles Omenihu

• 10

  Isaih Pacheco

• 81

  Nikko Remigio

• 30

  Christian Roland-Wallace

• 11

  Jalen Royals

• 71

  Josh Simmons

• 65

  Trey Smith

• 24

  Brashard Smith

• 9

  JuJu Smith-Schuster

• 76

  Kingsley Suamataia

• 74

  Jawaan Taylor

• 80

  Tyquan Thornton

• 99

  Jerry Tillery

• 85

  Robert Tonyan

• 23

  Drue Tranquill

• 96

  Marlon Tuipulotu

• 35

  Jaylen Watson

• 2

  Joshua Williams

• 20

  Nohl Williams

• 41

  James Winchester

• 1

  Xavier Worthy

Substitutes

Jacksonville Jaguars team news

The Jaguars are sweating on the status of Travon Walker. When the edge rusher left last week’s win over the 49ers with a wrist injury, it looked grim. Initial reports pegged him as week-to-week, but head coach Liam Coen upgraded him to day-to-day — meaning there’s a realistic shot he suits up Monday night. That would be a huge relief for a defense that has been Jacksonville’s calling card, already forcing 13 turnovers this season.

Elsewhere, linebacker Yasir Abdullah missed practice midweek, while wideout Dyami Brown (shoulder) and rookie lineman Wyatt Milum (knee) were limited. They were joined by a laundry list of banged-up starters, including Ezra Cleveland, Chuma Edoga, Anton Harrison, Patrick Mekari, Eric Murray, and Bhayshul Tuten.

The good news? Even with all the knocks and bruises, Jacksonville's identity remains clear: let Trevor Lawrence steer the ship, ride Travis Etienne in the run game, and let a takeaway-hungry defense tilt the field. Against Mahomes and the Chiefs, though, every inch will matter.

Getty Images

Kansas City Chiefs team news

The Chiefs head into Monday night with a mixed bag on the injury front. The concerning note is cornerback Kristian Fulton (ankle), who, for the second straight week, opened practice on a limited basis. Fulton suited up for the first two games of the year but hasn’t played since, leaving the secondary shorthanded.

The silver lining? Defensive end Michael Danna (quad), who sat out the Baltimore game, is back as a full participant. That’s a massive boost to Kansas City’s pass rush. Beyond that, the rest of the injury sheet looks clean — the other seven players on Thursday’s report were all full-go, meaning Andy Reid’s squad should be relatively close to full strength under the prime-time lights.

And speaking of strength, Patrick Mahomes reminded everyone why he’s still the face of the NFL. Against Baltimore, the two-time MVP tossed for 270 yards and four touchdowns, eclipsing 250 career TDs faster than anyone in league history. It wasn’t just efficient; it was vintage Mahomes, dragging a patchwork offense back to life.

Helping that revival was rookie spark plug Xavier Worthy, who made his first start of the season and immediately gave Kansas City’s attack a jolt. Worthy reeled in five catches for 83 yards, then showed off his versatility with 38 rushing yards and a score. If he’s the missing ingredient to rekindle the Chiefs’ explosiveness, the AFC better brace itself.

Getty Images

Watch and live stream Jaguars vs Chiefs in the USA

The Jaguars vs Chiefs game in Week 5 of the 2025 NFL season will be broadcast live on ABC/ESPN. Fans can catch the coverage onFubo (Try for free today!).

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More details on where to watch the game in the United States, including streaming options, will be released soon, so keep an eye out for our dedicated coverage.

Watch and live stream Jaguars vs Chiefs worldwide

For fans outside the U.S. looking to stay plugged into the action,NFL Game Pass on DAZN is the ultimate ticket. It serves up more than 200 regular-season and playoff matchups, complete Super Bowl coverage, plus access to NFL Network, NFL RedZone, and plenty more to keep you locked in all year long.

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To bypass regional restrictions or to access the game if you are travelling abroad, you can watch the action using a Virtual Private Network like ExpressVPN.

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How to buy Jaguars vs Chiefs tickets

The showdown between the Jaguars and the Chiefs is set for EverBank Stadium in Jacksonville, Florida, a venue that packs in up to 67,838 fans and promises a fiery atmosphere on game day.

Tickets are already up for grabs on StubHub, with entry starting at $386. From there, prices climb through the tiers — $300, $400, $500, $600, $700, $800, $900, $1,000, and stretching all the way into the premium ranges of $2,000, $3,000, $4,000, $5,000, $6,000, and topping out at $10,406 for the best seats in the house.

Check the link below for the full breakdown of how to purchase tickets to NFL games.

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READ MORE: NFL 2025 Tickets: Prices, deals, season tickets & membership information

Jaguars vs Chiefs Fantasy Football

What a difference seven days can make in the NFL. The Chiefs' offense looked flat and uninspired heading into Week 4, but the return of Xavier Worthy combined with a banged-up Baltimore defense was just the spark Kansas City needed. Suddenly, Patrick Mahomes feels right back in the thick of the QB1 fantasy conversation, especially with how shaky the position looks across the league.

What once looked like a one-man show is now morphing into a true committee. Kareem Hunt led the way last week with 44.3% of the snaps and 14 touches, though it only translated to 47 yards. Isiah Pacheco wasn’t far behind, logging 37.1% of the snaps and turning 9 touches into 48 yards—plus his first touchdown of the season through the air. Then there's Brashard Smith, who earned a bigger slice of the pie, seeing 25.7% of the snaps and contributing 36 yards on 7 touches. This is shaping up to be a frustrating three-headed situation for fantasy managers.

 Heading into last week, nobody quite knew how big a role Xavier Worthy would play, but he wasted no time reminding everyone why Kansas City drafted him. He was involved in over 70% of the team’s dropbacks, caught 5 of 8 targets for 83 yards, and added 38 yards on the ground with a pair of designed runs. That dual-threat ability makes him a dangerous weapon, and in fantasy terms, he’s planted firmly in high-end WR2 territory.

On the other side, the numbers paint a frustrating picture. Through four weeks, Trevor Lawrence hasn’t cracked QB1 territory once, and he’s barely sniffed mid-tier QB2 value. He averaged just 5.6 yards per attempt against Baltimore, and only once all year has he posted better than 6.5 Y/A. His season average of 5.9 ranks 28th in the league, and he’s completing nearly 9% fewer passes than expected—a brutal stat when you consider he’s faced the least pressure of any quarterback in football (22.7% of dropbacks). Right now, Lawrence is clinging to back-end QB2 status.

The one bright constant for Jacksonville has been Travis Etienne. He gashed Baltimore for 124 yards on 19 carries, highlighted by a 48-yard touchdown burst that showed off his elite acceleration. If the Jaguars keep feeding him like this, Etienne looks like a rock-solid RB2 with the ceiling to crack RB1 weeks.

Another week, another modest stat line. Brian Thomas Jr. hauled in 5 of 7 targets for 49 yards, keeping his WR2-level usage intact, but this passing attack is clearly holding him back. With Lawrence struggling and the aerial game sputtering, Thomas is hovering closer to the WR2/WR3 borderline until things turn around.

Jaguars vs Chiefs Game Predictions

The Jaguars had their shot to slam the door on San Francisco last week but left it ajar, and you can bet Patrick Mahomes won’t be so forgiving if they pull the same stunt on Monday night.

The Chiefs stumbled out of the gate with back-to-back defeats, but that feels like ancient history now. They stormed into Baltimore as field-goal underdogs and walked out with a commanding 37–20 win, fueled by Mahomes doing Mahomes things with a patchwork cast of wideouts and the electrifying Xavier Worthy.

Meanwhile, Jacksonville remains one of the league’s great riddles — inconsistent, unpredictable, but capable of pulling a rabbit out of the hat, as they did in upsetting the 49ers on the road.

The difference for Kansas City is simple: Worthy's return injected real juice into an offense that had been sputtering. And the scary part? They're still waiting on Rashee Rice. The Chiefs are looking more and more like the team we thought they were all along — not just contenders, but a group built to be back in the Super Bowl hunt.

Jaguars vs Chiefs Betting Odds

Spread

Chiefs -3.5 (-105)

Jaguars +3.5 (-115)

Moneyline

Chiefs -175

Jaguars +145

Total

OVER 46.5 (-110)

UNDER 46.5 (-110)

Form

Head-to-Head Record

JAX

Last 5 matches

KC

1

Win

0

Draws

4

Wins

• Jacksonville Jaguars

  26

  -

  13

  Kansas City Chiefs

• Jacksonville Jaguars

  9

  -

  17

  Kansas City Chiefs

• Kansas City Chiefs

  27

  -

  20

  Jacksonville Jaguars

• Kansas City Chiefs

  27

  -

  17

  Jacksonville Jaguars

• Jacksonville Jaguars

  26

  -

  40

  Kansas City Chiefs

Useful links

• Jaguars 2025 NFL schedule: TV channel, livestream & where to watch the games
• Chiefs 2025 NFL schedule: TV channel, livestream & where to watch the games
• How to watch and live stream NFL football for free and without cable
• 2025 fantasy football rankings: Running back (RB) | Wide receiver (WR) | Tight end (TE) | Quarterback (QB)