The Denver Broncos and Indianapolis Colts square off on Sunday, Sept. 14, at Lucas Oil Stadium as part of the Week 2 NFL slate.
Indianapolis (1-0) turned heads in its opener, steamrolling the Miami Dolphins 33-8 in a dominant showing.
Meanwhile, Denver (1-0) heads to Indy riding momentum of its own after grinding out a 20-12 win over the Tennessee Titans, aiming to keep its unbeaten record intact on the road.
| Date | Sunday, September 14, 2025 |
| Time | 4:05 pm ET / 1:05 pm PT / 10:05 am PT |
| Venue | Lucas Oil Stadium (Indianapolis, IN) |
| TV Channel | CBS |
| Streaming | Fubo (Try for free), Paramount+ |
| Buy Tickets | Stubhub |
| Odds | Broncos: -135 | Colts: +114 |
Indianapolis Colts vs Denver Broncos roster & injury news
Indianapolis Colts team news
As for the Colts, they couldn’t have scripted a better opening act. They dismantled Miami 33-8, controlling the ball for nearly 39 minutes and looking dominant in all three phases. Daniel Jones was sharp, completing 22 of 29 passes for 272 yards and a score, while Michael Pittman Jr. hauled in six catches for 80 yards and a touchdown.
Jonathan Taylor anchored the run game with 71 yards on 18 carries. Defensively, Indy was all over the Dolphins, led by Nick Cross and Charvarius Ward with six tackles apiece, plus three sacks and four tackles for loss.
| Position | Players |
|---|---|
| Offense | Daniel Jones, Riley Leonard, Anthony Richardson Sr. (QB); DJ Giddens, Tyler Goodson, Jonathan Taylor (RB); Josh Downs, Ashton Dulin, Anthony Gould, Adonai Mitchell, Alec Pierce, Michael Pittman Jr. (WR); Mo Alie-Cox, Will Mallory, Drew Ogletree, Tyler Warren (TE); Tanor Bortolini, Danny Pinter (C); Matt Goncalves, Quenton Nelson, Dalton Tucker (G); Bernhard Raimann, Braden Smith, Luke Tenuta, Jalen Travis (OT) |
| Defense | Samson Ebukam, Laiatu Latu, Tyquan Lewis, Kwity Paye, JT Tuimoloau (DE); Adetomiwa Adebawore, DeForest Buckner, Neville Gallimore, Eric Johnson II, Grover Stewart (DT); Joe Bachie, Zaire Franklin, Cameron McGrone, Chad Muma, Segun Olubi (LB); Mekhi Blackmon, Johnathan Edwards, Xavien Howard, Jaylon Jones, Kenny Moore II, Charvarius Ward (CB); Cam Bynum, Nick Cross, Daniel Scott, Rodney Thomas II (S) |
| Special Teams | Spencer Shrader (K), Rigoberto Sanchez (P), Luke Rhodes (LS) |
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Denver Broncos team news
Denver’s defense wasted no time making a statement in Week 1, piling up six sacks, 12 quarterback hits, and giving up the fewest points in a season opener since 2009. Now they’ll look to keep the pressure dialed up against Daniel Jones, who is set for his second start under center with Indianapolis.
Talanoa Hufanga shined in his Broncos debut with 10 tackles, seven of them solo, plus a forced fumble, while Zach Allen and Jonah Elliss teamed up for back-to-back sacks that swung momentum. That trio will be key again as Denver’s front looks to rattle Jones early.
On the other side of the ball, the Broncos are still searching for offensive consistency. Bo Nix flashed with a 22-yard strike to Courtland Sutton late in the second quarter last week, and Sean Payton has emphasized the need to establish the ground game with J.K. Dobbins and RJ Harvey. Against a defense that gave up just one touchdown and forced three turnovers in Week 1, finding that balance will be critical.
| Position | Players |
|---|---|
| Offense | Bo Nix, Jarrett Stidham (QB); Tyler Badie, J.K. Dobbins, RJ Harvey, Jaleel McLaughlin (RB); Pat Bryant, Troy Franklin, Marvin Mims Jr., Trent Sherfield Sr., Courtland Sutton (WR); Nate Adkins, Evan Engram, Lucas Krull, Adam Trautman (TE); Alex Forsyth, Luke Wattenberg (C); Quinn Meinerz, Ben Powers (G); Garett Bolles, Frank Crum, Mike McGlinchey, Alex Palczewski, Matt Peart (OT) |
| Defense | Zach Allen, John Franklin-Myers, Sai'vion Jones, Eyioma Uwazurike (DE); Jordan Jackson, D.J. Jones, Malcolm Roach (DT); Nik Bonitto, Jonathon Cooper, Jonah Elliss, Dre Greenlaw, Karene Reid, Que Robinson, Alex Singleton, Justin Strnad, Dondrea Tillman (LB); Kris Abrams-Draine, Jahdae Barron, Ja'Quan McMillian, Riley Moss, Pat Surtain II (CB); Talanoa Hufanga, Brandon Jones, Devon Key, P.J. Locke, JL Skinner (S) |
| Special Teams | Wil Lutz (PK); Jeremy Crawshaw (P); Mitchell Fraboni (LS) |
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Indianapolis Colts vs Denver Broncos head-to-head record
The Colts and Broncos have squared off 30 times over the years, postseason included, and the series couldn’t be tighter—each side has come away with 15 victories apiece. It’s a dead-even rivalry with no clear edge, adding even more intrigue to their next showdown.
Watch and live stream Colts vs Broncos in the USA
The Indianapolis Colts vs Denver Broncos game in Week 2 of the 2025 NFL season will be broadcast live nationally on CBS. Fans will be able to catch the coverage onFubo (Try for free today!) and Paramount+.
More details on where to watch the game in the United States, including streaming options, will be released soon, so keep an eye out for our dedicated coverage.
Watch and live stream Colts vs Broncos worldwide
For fans outside the U.S. looking to stay plugged into the action,NFL Game Pass on DAZN is the ultimate ticket. It serves up more than 200 regular-season and playoff matchups, complete Super Bowl coverage, plus access to NFL Network, NFL RedZone, and plenty more to keep you locked in all year long.
To bypass regional restrictions or to access the game if you are travelling abroad, you can watch the action using a Virtual Private Network like ExpressVPN.
How to buy Colts vs Broncos tickets
The showdown between the Colts and the Broncos is set for Lucas Oil Stadium in Indianapolis, IN , a venue that packs in up to 70,000 fans and promises a fiery atmosphere on game day.
Tickets are already up for grabs on StubHub, with entry starting at $386. From there, prices climb through the tiers — $300, $400, $500, $600, $700, $800, $900, $1,000, and stretching all the way into the premium ranges of $2,000, $3,000, $4,000, $5,000, $6,000, and topping out at $10,406 for the best seats in the house.
Check the link below for the full breakdown of how to purchase tickets to NFL games.
READ MORE: NFL 2025 Tickets: Prices, deals, season tickets & membership information
Indianapolis Colts vs Denver Broncos Fantasy Football
Daniel Jones was a hot commodity on the waiver wire after torching Miami in Week 1, but rolling him out against Denver feels like chasing fool's gold. The Broncos defense has been stingy against quarterbacks, giving up 17-plus fantasy points to just five signal-callers since the start of last season. In standard formats, Jones is best left on the bench, though he holds some value as a SuperFlex option.
Michael Pittman Jr. delivered a strong fantasy outing with 20 points in the opener, but his production is still tied closely to matchups, and drawing Patrick Surtain and Denver's secondary is a nightmare scenario. Dating back to last year, the Broncos have surrendered just 89.4 yards per game to perimeter wideouts, making Pittman a risky play in Week 2.
Colts vs Broncos Game Predictions
The Colts storm into Week 2 on a wave of momentum, with Daniel Jones firmly in charge after dismantling the Dolphins 33-8 at Lucas Oil Stadium.
On the other side, Bo Nix brings plenty of intrigue for fantasy managers and prop bettors alike, with a skill set that could turn heads if he finds his rhythm. Still, it's Denver's defense that looks poised to steal the spotlight. These underdogs aren’t just barking—they’re ready to bite. According to ESPN’s projection model, the Broncos are favored to leave Indy with the win in this Week 2 clash.
Colts vs Broncos Betting Odds
Spread
Broncos -2.5 (-110)
Colts +2.5 (-110)
Moneyline
Broncos: -135
Colts: +114
Total
42.5 (Over -110/Under -110)
More NFL news and coverage
- Colts 2025 NFL schedule: TV channel, livestream & where to watch the games
- Broncos 2025 NFL schedule: TV channel, livestream & where to watch the games
- How to watch and live stream NFL football for free and without cable
- 2025 fantasy football rankings: Running back (RB) | Wide receiver (WR) | Tight end (TE) | Quarterback (QB)