Week 1's Sunday Night Football slate serves up a heavyweight showdown as Lamar Jackson and the Baltimore Ravens travel north to face Josh Allen and the Buffalo Bills. It’s a marquee clash between two of the league’s most electrifying quarterbacks, and one that could easily stand as one of the premier matchups of the entire NFL season.
Baltimore’s 2024 campaign was impressive by nearly every measure. After stumbling out of the gate with back-to-back losses, the Ravens steadied themselves and finished 12-5, good enough to reclaim the AFC North crown. They opened the postseason with a convincing 28-14 win over archrival Pittsburgh in the Wild Card round but saw their run halted in the Divisional Playoffs, falling just short in a 27-25 thriller against Buffalo.
As for the Bills, they managed to outperform most preseason expectations. Buffalo put together a 13-4 record and captured yet another AFC East title—their fifth straight. They steamrolled Denver 31-7 in the Wild Card before outlasting Baltimore in that nail-biting Divisional matchup. Their momentum carried them to the AFC Championship, but the dream ended there with a narrow 32-29 defeat at the hands of the Kansas City Chiefs.
| Date | Sunday, September 7, 2025 |
| Time | 8:20 pm ET / 7:20 pm CT/ 5:20 pm PT |
| Venue | Highmark Stadium (Orchard Park, New York) |
| TV Channel | NBC |
| Streaming | Fubo, Peacock |
| Buy Tickets | Stubhub |
| Odds | -108 (Ravens) | +108 (Bills) |
Buffalo Bills vs Baltimore Ravens roster & injury news
Buffalo Bills team news
Things weren’t as smooth for Buffalo. The Bills stumbled out of the gate in a 34-25 loss to the New York Giants, surrendering points in every quarter despite a solid showing from Mike White, who tossed for 112 yards and two touchdowns on 8-of-13 passing.
Their struggles only deepened in the follow-up against Chicago, where they were shut out 38-0. Mitch Trubisky mustered just 55 passing yards, leaving Frank Gore Jr. to shoulder most of the production with 51 rushing yards and 30 more through the air.
| Position | Players |
|---|---|
| Offense | Josh Allen, Mitchell Trubisky (QB); James Cook, Ray Davis, Ty Johnson (RB); Reggie Gilliam (FB); Keon Coleman, Elijah Moore, Joshua Palmer, Curtis Samuel, Khalil Shakir, Tyrell Shavers (WR); Jackson Hawes, Dalton Kincaid, Dawson Knox (TE); Sedrick Van Pran-Granger (C); David Edwards, Connor McGovern, O'Cyrus Torrence (G); Alec Anderson, Spencer Brown, Dion Dawkins, Chase Lundt, Ryan Van Demark (OT) |
| Defense | Joey Bosa, AJ Epenesa, Michael Hoecht, Landon Jackson, Greg Rousseau, Javon Solomon (DE); DeWayne Carter, DaQuan Jones, Larry Ogunjobi, Ed Oliver, T.J. Sanders, Deone Walker (DT); Joe Andreessen, Terrel Bernard, Matt Milano, Shaq Thompson, Dorian Williams (LB); Christian Benford, Brandon Codrington, Jordan Hancock, Ja'Marcus Ingram, Taron Johnson, Cam Lewis, Dorian Strong, Tre'Davious White (CB); Cole Bishop, Damar Hamlin, Taylor Rapp (S) |
| Special Teams | Tyler Bass (PK); Brad Robbins (P); Reid Ferguson (LS) |
Baltimore Ravens team news
Baltimore kicked off its preseason slate on a high note, knocking off the Indianapolis Colts 24-16. Quarterback Devin Leary had a rough outing through the air, completing just 3-of-12 passes for 43 yards and an interception, but running back Keaton Mitchell picked up the slack with nine carries for 68 yards and a touchdown to spark the offense.
In their second exhibition matchup, the Ravens rolled past the Dallas Cowboys 31-13. Cooper Rush handled most of the work under center, throwing for 198 yards, a touchdown, and two picks on 20-of-30 passing, while Devontez Walker led the receiving corps with six receptions for 61 yards.
| Position | Players |
|---|---|
| Offense | Lamar Jackson, Cooper Rush (QB); Rasheen Ali, Derrick Henry, Justice Hill, Keaton Mitchell (RB); Patrick Ricard (FB); Rashod Bateman, Zay Flowers, DeAndre Hopkins, Devontez Walker, Tylan Wallace, LaJohntay Wester (WR); Mark Andrews, Charlie Kolar, Isaiah Likely (TE); Corey Bullock, Tyler Linderbaum (C); Ben Cleveland, Daniel Faalele, Andrew Vorhees (G); Joseph Noteboom, Roger Rosengarten, Ronnie Stanley, Carson Vinson (OT) |
| Defense | John Jenkins, Travis Jones, Nnamdi Madubuike, Aeneas Peebles, Broderick Washington Jr. (DT); Teddye Buchanan, Mike Green, Jay Higgins IV, Jake Hummel, David Ojabo, Odafe Oweh, Tavius Robinson, Trenton Simpson, Roquan Smith, Kyle Van Noy (LB); Jaire Alexander, Chidobe Awuzie, Marlon Humphrey, Keyon Martin, T.J. Tampa, Nate Wiggins (CB); Kyle Hamilton, Sanoussi Kane, Reuben Lowery III, Malaki Starks (S) |
| Special Teams | Tyler Loop (PK); Jordan Stout (P); Nick Moore (LS) |
Bills vs Ravens head-to-head record
The Ravens and Bills have squared off 13 times in their history, two of those clashes coming in the postseason. Baltimore holds a slim edge in the all-time series with seven victories, while Buffalo has claimed six.
Which channel is Bills vs Ravens game on?
The Buffalo Bills vs the Baltimore Ravens game in Week 1 of the 2025 NFL season will air live on NBC in the US. Streaming options are available on Fubo (in-market) and Peacock.
More details on where to watch the game in the United States, including streaming options, will be released soon, so keep an eye out for our dedicated coverage.
For fans outside the U.S. looking to stay plugged into the action,NFL Game Pass on DAZN is the ultimate ticket. It serves up more than 200 regular-season and playoff matchups, complete Super Bowl coverage, plus access to NFL Network, NFL RedZone, and plenty more to keep you locked in all year long.
How to buy Bills vs Ravens ticket
Tickets are already up for grabs on StubHub, with entry starting at $386. From there, prices climb through the tiers — $300, $400, $500, $600, $700, $800, $900, $1,000, and stretching all the way into the premium ranges of $2,000, $3,000, $4,000, $5,000, $6,000, and topping out at $10,406 for the best seats in the house.
Check the link below for the full breakdown of how to purchase tickets to NFL games.
READ MORE: NFL 2025 Tickets: Prices, deals, season tickets & membership information
Bills vs Ravens Fantasy Football
Lamar Jackson slots in as a strong QB2 for fantasy managers this week, carrying a 21.9-point projection thanks to his explosive dual-threat skill set that allows him to hurt defenses both in the air and on the ground. Across the field, Josh Allen sits at QB4 with a trickier assignment against Baltimore's reinforced secondary, but his overall upside and weekly ceiling keep him locked in as an every-week starter.
In the backfield, Derrick Henry remains a workhorse and a top-10 fantasy back, projected at 16.1 points as the centerpiece of Baltimore’s offense. Meanwhile, James Cook finds himself in a tough spot, ranked RB18 and staring down a stout Ravens front, compounded by questions about his conditioning following his holdout.
Through the air, Zay Flowers offers WR18 value and should benefit from steady target volume, while Buffalo’s Khalil Shakir and Keon Coleman enter Week 1 as risky WR3/flex options given their difficult matchups against Baltimore’s corners. At tight end, Mark Andrews sits as TE4 and remains a high-value option in a featured role, whereas Dalton Kincaid lands at TE15, carrying more volatility. Defensively, neither side projects well for fantasy purposes, making both units fade candidates in streaming lineups.
Fantasy Takeaways:
- Fire up Lamar Jackson as a high-end QB2 with elite upside.
- Trust Derrick Henry as a reliable RB1 anchor.
- Keep Josh Allen locked into lineups, but lower expectations against Baltimore’s secondary.
- Zay Flowers and Mark Andrews should be viewed as must-start pass-catchers.
- Treat Khalil Shakir and Keon Coleman as dart throws in WR3/flex spots.
- Approach James Cook cautiously given the matchup and offseason concerns.
- Steer clear of both defenses as fantasy starters this week.
Bills vs Ravens Game Predictions
Jackson wastes no time finding his rhythm, and Baltimore opens the campaign with a statement victory, flipping the script from last year’s heartbreak. The Ravens silence the Buffalo faithful and nudge ahead in the head-to-head history, now 8-6 in their favor.
Meanwhile, Derrick Henry proves nearly unstoppable, rumbling for triple-digit yardage and punching in at least one score, powered by the steady protection of standout left tackle Ronnie Stanley.
Oddsmakers see this one as nearly a coin flip, but they’re leaning slightly toward Buffalo. The Bills enter Sunday Night Football with a 52.3% probability of coming out on top, while the Ravens are pegged with a 47.3% chance of stealing the opener. A razor-thin margin remains for the rare possibility of a draw.
Bills vs Ravens Odds
Spread: Bills -1.5 (+100), Ravens +1.5 (-122)
Total: 50.5 (Over -115/Under -105)
Moneyline: -108 (Ravens) | +108 (Bills)
More NFL news and coverage
- Bills 2025 NFL schedule: TV channel, livestream & where to watch the games
- Baltimore Ravens 2025 NFL schedule: TV channel, livestream & where to watch the games
- How to watch and live stream NFL football for free and without cable
- 2025 fantasy football rankings: Running back (RB) | Wide receiver (WR) | Tight end (TE) | Quarterback (QB)