Isak's goal at Tottenham was just his second in the Premier League since his £125 million ($166m) move from Newcastle on deadline day of the summer transfer window, with his only other strike coming in a 1-0 win at West Ham on November 30.
The Swede has been rotated in and out of Slot's starting lineup all season long, with fellow summer arrival Hugo Ekitike splitting the minutes as the No.9. Unlike Isak, Ekitike has proven a hit at Anfield so far, scoring 10 times for Liverpool in all competitions already. He scored the Reds' second against Spurs, rising above Cristian Romero to head home a deflected cross from Frimpong.
Star forward Mohamed Salah is currently at the Africa Cup of Nations with Egypt, while there is increasing speculation that Harvey Elliott could return to the club in January having failed to make an impact on loan at Aston Villa.