So, Acerbi sought professional help. It helped him realise that he only needed people around him that he both loved and trusted. He began to understand what he really wanted out of life. "Without cancer, I would have retired at 28," he told Gazzetta. "Perhaps I would be in Serie B, at Cittadella, but after cancer, my real life began, giving me a second chance."
One which he has taken with open arms. His fine form at Sassuolo earned him a move to Lazio in 2018, and he became a stalwart in the Biancocelesti back-line, as well as playing his part in Italy's shock triumph at Euro 2020.
His time at Stadio Olimpico came to an acrimonious end, though. After a poor start to the 2021-22 season, he made a 'shushing' gesture towards the Lazio fans that had been booing him and his team-mates after scoring against Genoa. It was a mistake. Acerbi realised that right away and he apologised, but the supporters weren't appeased.
"It wasn't enough," he later lamented in an interview with Corriere dello Sport. "At that moment, something broke." And there would be no fixing his relationship with the fans. Indeed, the longer the season went on, the worse it got, with Acerbi even having to pen an open letter to the Lazio faithful after being slated for seemingly laughing after the concession of a late goal to AC Milan in April 2022.
It was clear that he needed to leave, even though Maurizio Sarri was desperate for him to stay. The coach had even defended him from furious fans who interrupted a pre-season training session last summer. But Acerbi's mind was already made up. He wanted out - not least because not everyone at Lazio had been as supportive as Sarri.
"In the last year I have had to eat a lot of sh*t," he told the Corriere. "I made one mistake, but that’s worth five compared to the 95 I had to swallow. I still went about my business, not giving a damn. And I am very proud of that. Others, in my place, would have quit much earlier.
"But I expected the club to defend me, absolutely. You can make mistakes, but the club has to protect you in public. Even if they slaughter you in private."