It has been an excellent week for Sevilla as the Andalusians followed up their first leg victory in this tie with a comfortable 3-0 win at Espanyol in La Liga at the weekend.
Vincenzo Montella's side became the first Spanish team to win a game at Atletico's new Wanda Metropolitano stadium and that 2-1 first leg success puts them in a strong position to make the semi finals of the Copa del Rey.
Atleti, meanwhile, had another disappointing result on Saturday in La Liga - drawing 1-1 at home to league debutants Girona - and Diego Simeone's side head to the Estadio Sanchez Pizjuan with a point to prove.
Match odds
Sevilla are generally excellent in their home stadium and the defeat in the Seville Derby against Real Betis in their last home game was their first home league defeat in 14 months.
Getty ImagesIn the cup they are undefeated at home since 2013, winning ten and drawing one of their last 11 games, therefore the price therefore of 2/1 (3.00) offered by Paddy Power for a home win looks to offer potential value.
Atleti, on the other hand, are available at 11/8 (2.38) and the draw can be backed at 23/10 (3.30).
Team news
Montella fielded the same starting eleven against Espanyol as he had at the Wanda Metropolitano, but the manager is unlikely to name an unchanged team for the third game in six days.
Diego Simeone, for his part, took off Diego Costa and Antoine Griezmann in the second half against Girona with one eye on this match, so both are likely to start in another strong looking Atletico eleven.
Chances likely at both ends at the Sanchez Pizjuan
Sevilla are a side that can generally be relied upon for goals, especially at home, but they do concede a lot of chances; indeed, against Espanyol they kept a clean sheet but only because of some extremely wasteful finishing from their opponents.
Their last clean sheet at home was against Levante, who are one of the poorest sides in the division but still managed to have nine shots on goal during the match and Atletico will fancy their chances of scoring.
Of course, Simeone's side need to net twice on Tuesday to have any chance of progressing and that need for goals should lead them to approaching the game in a more open way than usual.
Tips and predictions
Both teams to score has paid out in six of Sevilla's last nine home matches in all competitions and is offered at 8/11 (1.73), which looks like a solid selection given the 2-1 scoreline from the first leg.
Both teams to score at 8/11 (1.73) for a 3pt stake with Paddy Power