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Best Champions League soccer bets of the week: Picks, odds & more

The Champions League returns this week as the remaining last-16 ties are set to be concluded.

On Tuesday, Ajax host Benfica with the two teams level at 2-2 on aggregate while Manchester United and Atletico Madrid meet after playing out a 1-1 draw in Spain.

The following day, Villarreal travel to Juventus with the two teams tied at 1-1 and Chelsea look to defend their 2-0 lead at Lille.

All odds from bet365.

Tuesday's best Champions League bets

Ajax odds

-275

Benfica odds

+600

Draw odds

+450

Over/under 2.5 goals odds

-300/+240

Ajax are the favorite to beat Benfica at the Johan Cruyiff Arena on Tuesday.

But the Dutch team has hardly been at its best defensively lately. They recently needed a stoppage time goal from Ryan Gravenberch to restore their lead and win 3-2 against Cambuur.

A week prior, they had to come back from two goals down to beat RKC Waalwijk 3-2, a result that came just a week after they were beaten 2-1 by Go Ahead Eagles.

Their opponents are in good form lately, however, despite a 1-1 draw against Vizela at the weekend.

As a result, rolling with Benfica as a surprise underdog pick could be the right move if you're feeling adventurous.

And with both teams looking to get the result over the line, they could come at each other again on Tuesday and backing over 2.5 goals at odds of -300 looks a smart bet.

Manchester United odds

+115

Atletico Madrid odds

+275

Draw odds

+210

Over/under 2.5 goals odds

+120/-150

Manchester United registered their first win in four games at the weekend as they beat Tottenham 3-2 thanks to a Cristiano Ronaldo hat-trick.

Atletico Madrid, meanwhile, have won all three of their matches since the 1-1 draw with United in the Spanish capital.

The two teams were evenly matched in the first leg and could be impossible to separate at the end of 90 minutes this time around, too.

At odds of +210, betting these two teams to draw and be forced to take the tie into extra-time is an enticing choice.

Wednesday's best Champions League bets

Juventus odds

-106

Villarreal odds

+320

Draw odds

+240

Over/under 2.5 goals

+110/-138

Juventus are on a four-game winning run since they were held to a draw at Villarreal.

The Spanish side, meanwhile, remain fairly inconsistent and sit in seventh place in La Liga.

Despite the injury problems facing Massimiliano Allegri's team, the home side is favorited to progress to the quarterfinals of the competition and look worthy of making it five consecutive victories.

You can get favorable odds of -106 for Juventus to win the second-leg and thus the tie.

Lille odds

+320

Chelsea odds

-110

Draw odds

+250

Over/under 2.5 goals odds

-110/-110

It has been a difficult period for Chelsea for off-field reasons, but Thomas Tuchel's team remains strong throughout the adversity.

The Blues have a big advantage from the first-leg after winning 2-0 at Stamford Bridge and will be confident of finishing the job in France.

Chelsea have won all of the last four matches, while Lille were held to a goalless draw against Saint-Etienne on Friday.

Chelsea should prove too strong for the Ligue 1 team once again and may prove impenetrable once again, so odds of -106 against both teams scoring make it a good bet.

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