The North Africans face-off with the five-time champions who have progressed from seven of their nine Afcon semi-final matches
Egypt's head coach, Carlos Queiroz, has revealed his starting XI to face Cameroon in an Africa Cup of Nations semi-final game on Thursday at the Paul Biya Stadium in Yaounde.
Here is how they line up:
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Goalkeeper: Mohamed Abou Gabal
After he was injured during the Morocco game, Gabal returns as Mohamed Sobhy drops to the bench.
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Right-back - Omar Kamal
Kamal has been a solid figure for Egypt at the back and his ability to add numbers upfront when they are in attacking mode should give the record giants an added advantage.
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Centre-back - Mohamed Abdelmonem
Abdelmonem keeps his place as the Pharaohs face Cameroon for what will be the 11th Afcon encounter between them.
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Centre-back - Mahmoud Hamdy
Hamdy replaces Ayman Ashraf, who has a yellow card from the Morocco quarter-final game.
Together with Abdelmonem, they need to be careful enough when dealing with in-form Cameroon captain Vincent Aboubakar and Karl Toko Ekambi.
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Left-back - Ahmed Abou El Fotouh
His performance against the Atlas Lions stood out, and given the stakes the semi-final carries, El Fotouh is expected to perform even better.
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Midfielder - Hamdy Fathy
As Egypt hope to win four of their last five Afcon games against the Indomitable Lions, Fathy has been drafted into the starting team ahead of Mahmoud Trezeguet, who came on in the second half against Morocco.
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Midfielder - Amr El Solia
The start means El Solia has featured in four of five games for the Pharaohs, and his solidity and experience in midfield should be key for the African giants.
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Midfielder - Mohamed Elneny
Another consistent member of Egypt's first eleven, and the Arsenal forward is expected to offer not only a top performance but also leadership as he is among the most experienced stars in the squad.
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Forward - Mohamed Salah
His goal and assist against Morocco should act as morale-boosting factor as he hopes to lead the former champions past the hosts and into the final stage of the Afcon's 33rd edition.
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Striker - Mostafa Mohamed
Despite the fact he has struggled for goals, the technical bench has kept their faith in Mohamed as he is among the attackers once more.
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Forward - Omar Marmoush
Marmoush starts ahead of Ahmed Zizo who replaced him in the 80th minute against Morocco in the Round of 16 showdown.