The Rossoneri hope to make it past the Czech club and into the quarter-finals of the Europa League for the first time. The last time they progressed beyond the last 16 of Europe's second-tier competition was in 2001-02, when they reached the final four of the UEFA Cup.
Still, Pioli believes his team can go on to claim the title, saying: "You have to think you can win this cup, then it's clear that in addition to thinking that, you need to demonstrate skills. The team is doing well but now there's a complex obstacle to face. We certainly all have a chance of doing well."