The striker who fired blank in his last outing against Chievo returned to goalscoring action against Simone Inzaghi's side, equalising Senad Lulic's opener.
Just before the half-hour mark, Nwankwo benefitted from a Bruno Martella assist to pull the Pythagoreans levelled after they went down to a Lulic's penalty in the 17th minute.
Federico Ceccherini's 64th-minute effort looked like the winner for the hosts until Sergej Milinkovi-Savic's late strike ensured Walter Zenga's men shared the spoils; a result which did not help their aim of getting off the relegation zone.
Crotone
Coach Zenga will be looking up to his lanky forward who has scored seven goals in 22 appearances for inspiration when they travel to Naples next week.