Jose Mourinho is far from pleased with the English FA's medical team after their handling of Phil Jones.
The Portuguese, who says he has not spoken to England boss Gareth Southgate on the matter, claims he's never seen anything of the sort in his career.
"I have been a manager since 2000 and in 17 years I don't have one single player that had injections of anaesthetic to play a friendly. Never. Never," he told a press conference.
"I am not an angel and I had players be injected to play official matches, crucial matches but a friendly -- to get six local anaesthetic injections to play a friendly, I've never heard of that.
"But Phil Jones had it and had it before the match and after 25 minutes he was out and he is out [against Newcastle].
"I am just telling a fact. He was injected in the afternoon of the match, he didn't feel good during the warm up. Between the warm up and the start of the match he had five more local injections to play the friendly."
While the club will have to do without the services of Jones, Mourinho will be able to rely on several players who are returning from injury.
The former Real Madrid and Chelsea boss confirmed on Friday that Marcos Rojo, Paul Pogba and Zlatan Ibrahimovic were all available for Saturday's matchday squad, though Mourinho made it clear that Ibrahimovic won't be in the starting side.
The Old Trafford outfit sit second in the table, eight points back of Manchester rivals City, and take on a Newcastle side that have picked up just one win in their last six.